Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.
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The many faces of aire in central toleranceExpression of the autoimmune regulator gene and its relevance to the mechanisms of central and peripheral toleranceSubcellular localization of the autoimmune regulator protein. characterization of nuclear targeting and transcriptional activation domainMutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy proteinTranscriptional regulation by AIRE: molecular mechanisms of central toleranceAutoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED): a model disease to study molecular aspects of endocrine autoimmunityUbiquitin in the immune systemThe solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylationThe autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding proteinAPECED mutations in the autoimmune regulator (AIRE) geneSelf-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organsModulation of Aire regulates the expression of tissue-restricted antigensAutoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytesAire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-toleranceTSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentationSubcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED)Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1Thymus transplantation for complete DiGeorge syndrome: European experience.Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cellsAIRE deficiency in thymus of 2 patients with Omenn syndrome.Expression of thyrotropin receptor, thyroglobulin, sodium-iodide symporter, and thyroperoxidase by fibrocytes depends on AIRE.Control of central and peripheral tolerance by Aire.Molecular mimicry and autoimmune liver disease: virtuous intentions, malign consequences.APECED: A Paradigm of Complex Interactions between Genetic Background and Susceptibility FactorsAutoimmune regulator (AIRE) gene on chromosome 21: implications for autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) any more common manifestations of endocrine autoimmunity.Autoimmune regulator: from loss of function to autoimmunity.Central and peripheral autoantigen presentation in immune tolerance.On the pathogenesis of autoimmune thyroid disease: a unifying hypothesis.Genetic basis of autoimmunity.Anticommensal Responses Are Associated with Regulatory T Cell Defect in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients.An innately interesting decade of research in immunology.β-catenin activation drives thymoma initiation and progression in miceRank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.Genetic lesions in T-cell tolerance and thresholds for autoimmunity.Emerging treatment options for patients with recurrent advanced thymic epithelial tumorsImmunity by ubiquitylation: a reversible process of modification.AIRE functions as an E3 ubiquitin ligaseGene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire.The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription.
P2860
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P2860
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Autoimmune regulator is expres ...... e tolerance in thymus medulla.
@en
Autoimmune regulator is expres ...... e tolerance in thymus medulla.
@nl
type
label
Autoimmune regulator is expres ...... e tolerance in thymus medulla.
@en
Autoimmune regulator is expres ...... e tolerance in thymus medulla.
@nl
prefLabel
Autoimmune regulator is expres ...... e tolerance in thymus medulla.
@en
Autoimmune regulator is expres ...... e tolerance in thymus medulla.
@nl
P2093
P50
P356
P1476
Autoimmune regulator is expres ...... ne tolerance in thymus medulla
@en
P2093
Lagerstedt A
Nagamine K
Nieminen M
P304
P356
10.1006/BBRC.1999.0308
P407
P577
1999-04-01T00:00:00Z