Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.
about
Construction and analysis of a modular model of caspase activation in apoptosisThe Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timerThe holo-apoptosome: activation of procaspase-9 and interactions with caspase-3Caspases: pharmacological manipulation of cell deathPharmacological manipulation of cell death: clinical applications in sight?Upstream regulatory role for XIAP in receptor-mediated apoptosisBcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapyCaspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9Engineering a dimeric caspase-9: a re-evaluation of the induced proximity model for caspase activationApoptosis in uterine epithelium and decidua in response to implantation: evidence for two different pathwaysRegulatory T Cells: Molecular Actions on Effector Cells in Immune RegulationProtease signalling: the cutting edgeThe modulation of apoptosis by oncogenic virusesAtomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1The structure of Aip1p, a WD repeat protein that regulates Cofilin-mediated actin depolymerizationRapid Folding and Unfolding of Apaf-1 CARDStructure of the Drosophila Apoptosome at 6.9 Å ResolutionA Class of Allosteric Caspase Inhibitors Identified by High-Throughput ScreeningChanges in Apaf-1 Conformation That Drive Apoptosome AssemblyStructure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome AssemblyInitiation and perpetuation of NLRP3 inflammasome activation and assemblyDNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenanceNALPs: a novel protein family involved in inflammationStructure of the apoptotic protease-activating factor 1 bound to ADPProcaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspase-activating compound 1 (PAC-1) and its cellular co-localization with caspase-3Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9Role of Apaf-1, a key regulator of apoptosis, in melanoma progression and chemoresistanceHealth and cellular impacts of air pollutants: from cytoprotection to cytotoxicityFerricytochrome c protects mitochondrial cytochrome c oxidase against hydrogen peroxide-induced oxidative damageBax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranesMultiple Domain Associations within the Arabidopsis Immune Receptor RPP1 Regulate the Activation of Programmed Cell DeathThe Fas/Fas ligand death receptor pathway contributes to phenylalanine-induced apoptosis in cortical neuronsJun kinase delays caspase-9 activation by interaction with the apoptosomeActivation and regulation of the inflammasomesStructural features of caspase-activating complexesLoss of VOPP1 overexpression in squamous carcinoma cells induces apoptosis through oxidative cellular injury.Mechanisms of rapid sensory hair-cell death following co-administration of gentamicin and ethacrynic acid.Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes.
P2860
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P2860
Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Three-dimensional structure of ...... ase-9 binding, and activation.
@en
Three-dimensional structure of ...... ase-9 binding, and activation.
@nl
type
label
Three-dimensional structure of ...... ase-9 binding, and activation.
@en
Three-dimensional structure of ...... ase-9 binding, and activation.
@nl
prefLabel
Three-dimensional structure of ...... ase-9 binding, and activation.
@en
Three-dimensional structure of ...... ase-9 binding, and activation.
@nl
P2093
P1433
P1476
Three-dimensional structure of ...... ase-9 binding, and activation.
@en
P2093
David Gene Morgan
Devrim Acehan
John E Heuser
Xiaodong Wang
Xuejun Jiang
P304
P356
10.1016/S1097-2765(02)00442-2
P577
2002-02-01T00:00:00Z