Structural and functional analysis of ataxin-2 and ataxin-3.
about
Machado-Joseph Disease: from first descriptions to new perspectives.Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granulesAtaxin-2-like is a regulator of stress granules and processing bodiesAn arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymesAtaxin-2 regulates RGS8 translation in a new BAC-SCA2 transgenic mouse modelStructure prediction of polyglutamine disease proteins: comparison of methods.The Protein Structure Context of PolyQ RegionsTherapeutic prospects for spinocerebellar ataxia type 2 and 3.Trinucleotide repeats: a structural perspectiveElongation kinetics of polyglutamine peptide fibrils: a quartz crystal microbalance with dissipation study.The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4Ataxin-3 expression correlates with the clinicopathologic features of gastric cancerThe solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition.Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain.Roles of ataxin-2 in pathological cascades mediated by TAR DNA-binding protein 43 (TDP-43) and Fused in Sarcoma (FUS)Functional interactions as a survival strategy against abnormal aggregationCharacterization of the conformational fluctuations in the Josephin domain of ataxin-3.Role of inositol 1,4,5-trisphosphate receptors in pathogenesis of Huntington's disease and spinocerebellar ataxiasLocation trumps length: polyglutamine-mediated changes in folding and aggregation of a host proteinAggregation kinetics of interrupted polyglutamine peptidesAllosteric regulation of deubiquitylase activity through ubiquitination.RNA-binding protein misregulation in microsatellite expansion disordersAnalysis of stress granule assembly in Schizosaccharomyces pombe.Targeting intrinsically disordered proteins in neurodegenerative and protein dysfunction diseases: another illustration of the D(2) concept.Lsm proteins and Hfq: Life at the 3' endDe novo mutations in ataxin-2 gene and ALS risk.Inositol 1,4,5-tripshosphate receptor, calcium signaling, and polyglutamine expansion disorders.Evolutionary diversification of the Sm family of RNA-associated proteins.Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2.Examining polyglutamine peptide length: a connection between collapsed conformations and increased aggregation.Drosophila ataxin-2 gene encodes two differentially expressed isoforms and its function in larval fat body is crucial for development of peripheral tissuesOxidative stress as a cofactor in spinocerebellar ataxia type 2.Spinocerebellar ataxia type 2: clinical presentation, molecular mechanisms, and therapeutic perspectives.Stress granules in neurodegeneration--lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma.Ataxin-3 protein and RNA toxicity in spinocerebellar ataxia type 3: current insights and emerging therapeutic strategies.RNA metabolism in ALS: when normal processes become pathological.Casein kinase 2 interacts with and phosphorylates ataxin-3.The Multiple Faces of Spinocerebellar Ataxia type 2.Ataxin-2 mediated cell death is dependent on domains downstream of the polyQ repeat.
P2860
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P2860
Structural and functional analysis of ataxin-2 and ataxin-3.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Structural and functional analysis of ataxin-2 and ataxin-3.
@en
Structural and functional analysis of ataxin-2 and ataxin-3.
@nl
type
label
Structural and functional analysis of ataxin-2 and ataxin-3.
@en
Structural and functional analysis of ataxin-2 and ataxin-3.
@nl
prefLabel
Structural and functional analysis of ataxin-2 and ataxin-3.
@en
Structural and functional analysis of ataxin-2 and ataxin-3.
@nl
P50
P1433
P1476
Structural and functional analysis of ataxin-2 and ataxin-3.
@en
P2093
Mario Albrecht
P304
P356
10.1111/J.1432-1033.2004.04245.X
P407
P577
2004-08-01T00:00:00Z