Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model.

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Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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2018年學術文章

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name

Recombinant methioninase combi ...... xenograft (PDOX) mouse model.

@en

Recombinant methioninase combined with doxorubicin

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type

Item

label

Recombinant methioninase combi ...... xenograft (PDOX) mouse model.

@en

Recombinant methioninase combined with doxorubicin

@nl

prefLabel

Recombinant methioninase combi ...... xenograft (PDOX) mouse model.

@en

Recombinant methioninase combined with doxorubicin

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P1476

Recombinant methioninase combi ...... xenograft (PDOX) mouse model.

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P2093

Arun S Singh

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Emily Gainor

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Fritz C Eilber

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Hiroaki Kimura

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Hiromichi Oshiro

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Hiroyuki Tsuchiya

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Katsuhiro Hayashi

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Kei Kawaguchi

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Kentaro Miyake

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Mark A Eckardt

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P2860

Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.

Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells.

Matching targets for selective cancer therapy.

Selective methioninase-induced trap of cancer cells in S/G2 phase visualized by FUCCI imaging confers chemosensitivity.

Overview of sarcomas in the adolescent and young adult population.

Chemotherapy is associated with improved survival in adult patients with primary extremity synovial sarcoma.

Metastatic recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) nude mouse model is inhibited by neoadjuvant chemotherapy in combination with fluorescence-guided surgery with an anti-CA 19-9-conjugated fluorophore.

High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine.

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models.

Establishment of a patient-derived orthotopic Xenograft (PDOX) model of HER-2-positive cervical cancer expressing the clinical metastatic pattern.

P304

19263-19272

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scholarly article

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10.18632/ONCOTARGET.24996

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English

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P50

Kentaro Igarashi

Shinji Miwa

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2018-04-10T00:00:00Z

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P698

29721200

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P921

xenograft

P932

5922394

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