about
DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADDIdentification of CHIP as a novel causative gene for autosomal recessive cerebellar ataxiaHax-1 is rapidly degraded by the proteasome dependent on its PEST sequence.Oxidized DJ-1 interacts with the mitochondrial protein BCL-XL.Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia.Parkin represses 6-hydroxydopamine-induced apoptosis via stabilizing scaffold protein p62 in PC12 cells.Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO miceL166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL.TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion.P7C3 inhibits GSK3β activation to protect dopaminergic neurons against neurotoxin-induced cell death in vitro and in vivo.Bcl-2 Decreases the Affinity of SQSTM1/p62 to Poly-Ubiquitin Chains and Suppresses the Aggregation of Misfolded Protein in Neurodegenerative Disease.Ataxin-3 protects cells against H2O2-induced oxidative stress by enhancing the interaction between Bcl-X(L) and Bax.Genomic variants at 20p11 associated with body fat mass in the European population.NGFI-B nuclear orphan receptor Nurr1 interacts with p53 and suppresses its transcriptional activity.Sumoylation is critical for DJ-1 to repress p53 transcriptional activity.Regulation of autophagic flux by CHIP.Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases.DJ-1, a cancer and Parkinson's disease associated protein, regulates autophagy through JNK pathway in cancer cells.Dendritic cell nuclear protein-1 regulates melatonin biosynthesis by binding to BMAL1 and inhibiting the transcription of N-acetyltransferase in C6 cells.Familial Parkinson's Disease-Associated L166P Mutant DJ-1 is Cleaved by Mitochondrial Serine Protease Omi/HtrA2.Phosphodiesterase 10A inhibition attenuates sleep deprivation-induced deficits in long-term fear memory.Tyrosine hydroxylase down-regulation after loss of Abelson helper integration site 1 (AHI1) promotes depression via the circadian clock pathway in mice.P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death andDysbindin-1, a schizophrenia-related protein, facilitates neurite outgrowth by promoting the transcriptional activity of p53Pharmacological activation of REV-ERBα represses LPS-induced microglial activation through the NF-κB pathwayLoss of VAPB Regulates Autophagy in a Beclin 1-Dependent MannerMotor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PRPoly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent EndocytosisDJ-1 regulates tyrosine hydroxylase expression through CaMKKβ/CaMKIV/CREB1 pathway in vitro and in vivo
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Haigang Ren
@ast
Haigang Ren
@en
Haigang Ren
@es
Haigang Ren
@nl
Haigang Ren
@sl
type
label
Haigang Ren
@ast
Haigang Ren
@en
Haigang Ren
@es
Haigang Ren
@nl
Haigang Ren
@sl
prefLabel
Haigang Ren
@ast
Haigang Ren
@en
Haigang Ren
@es
Haigang Ren
@nl
Haigang Ren
@sl
P106
P31
P496
0000-0001-8844-4754