Age-Related Increase of Insulin-Degrading Enzyme Is Inversely Correlated with Cognitive Function in APPswe/PS1dE9 Mice.

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Age-Related Increase of Insulin-Degrading Enzyme Is Inversely Correlated with Cognitive Function in APPswe/PS1dE9 Mice.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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Age-Related Increase of Insuli ...... unction in APPswe/PS1dE9 Mice.

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Age-Related Increase of Insuli ...... unction in APPswe/PS1dE9 Mice.

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Age-Related Increase of Insuli ...... unction in APPswe/PS1dE9 Mice.

@en

Age-Related Increase of Insuli ...... unction in APPswe/PS1dE9 Mice.

@nl

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Age-Related Increase of Insuli ...... unction in APPswe/PS1dE9 Mice.

@en

Age-Related Increase of Insuli ...... unction in APPswe/PS1dE9 Mice.

@nl

P1476

Age-Related Increase of Insuli ...... Function in APPswe/PS1dE9 Mice

@en

P2093

Peichang Wang

http://www.w3.org/2001/XMLSchema#string

Yi Zhang

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P2860

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease.

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

Sharing data in the global alzheimer's association interactive network

Mechanisms underlying insulin deficiency-induced acceleration of β-amyloidosis in a mouse model of Alzheimer's disease

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

Decreased clearance of CNS beta-amyloid in Alzheimer's disease

MRI of the 'Alzheimer syndrome'.

Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.

P304

2446-2455

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P31

scholarly article

P356

10.12659/MSM.909596

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P478

http://www.w3.org/2001/XMLSchema#string

P577

2018-04-22T00:00:00Z

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P698

29680859

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P932

5935016

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