Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody.

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Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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Decreased osteoprogenitor prol ...... ated with sclerostin antibody.

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Decreased osteoprogenitor prol ...... ated with sclerostin antibody.

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label

Decreased osteoprogenitor prol ...... ated with sclerostin antibody.

@en

Decreased osteoprogenitor prol ...... ated with sclerostin antibody.

@nl

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Decreased osteoprogenitor prol ...... ated with sclerostin antibody.

@en

Decreased osteoprogenitor prol ...... ated with sclerostin antibody.

@nl

P1476

Decreased osteoprogenitor prol ...... ated with sclerostin antibody.

@en

P2093

Danielle Brown

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Ian Pyrah

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Kathrin Locher

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Melanie Felx

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Michael S Ominsky

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Nacera Mellal

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Rogely Waite Boyce

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Scott Taylor

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P2860

Novel approaches for two and three dimensional multiplexed imaging of osteocytes.

A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy.

Transcriptional Profiling of Laser Capture Microdissected Subpopulations of the Osteoblast Lineage Provides Insight Into the Early Response to Sclerostin Antibody in Rats.

Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats.

Romosozumab Improves Bone Mass and Strength While Maintaining Bone Quality in Ovariectomized Cynomolgus Monkeys.

Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation.

Regulation of hematopoiesis in endosteal microenvironments.

Differential temporal effects of sclerostin antibody and parathyroid hormone on cancellous and cortical bone and quantitative differences in effects on the osteoblast lineage in young intact rats.

Kinetic reconstruction reveals time-dependent effects of romosozumab on bone formation and osteoblast function in vertebral cancellous and cortical bone in cynomolgus monkeys.

Carcinogenicity risk assessment of romosozumab: A review of scientific weight-of-evidence and findings in a rat lifetime pharmacology study.

P304

90-94

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P31

scholarly article

P356

10.1016/J.BONR.2018.03.001

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P478

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P577

2018-03-03T00:00:00Z

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29955626

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P932

6020110

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