about
BACE-1 inhibitors part 2: identification of hydroxy ethylamines (HEAs) with reduced peptidic characterBACE-1 inhibitors part 1: identification of novel hydroxy ethylamines (HEAs)BACE-1 inhibitors part 3: identification of hydroxy ethylamines (HEAs) with nanomolar potency in cellsSecond generation of BACE-1 inhibitors part 3: Towards non hydroxyethylamine transition state mimeticsSecond generation of BACE-1 inhibitors part 2: Optimisation of the non-prime side substituentCharacterization of the glycosylation profiles of Alzheimer's beta -secretase protein Asp-2 expressed in a variety of cell lines.Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT).TIMP-3 inhibition of ADAMTS-4 (Aggrecanase-1) is modulated by interactions between aggrecan and the C-terminal domain of ADAMTS-4.Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT).Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification.Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36An abundantly secreted glycoprotein from Drosophila melanogaster is related to mammalian secretory proteins produced in rheumatoid tissues and by activated macrophages.Analysis of the interaction between human interleukin-5 and the soluble domain of its receptor using a surface plasmon resonance biosensor.Nucleosome Binding Alters the Substrate Bonding Environment of Histone H3 Lysine 36 Methyltransferase NSD2.
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P50
description
hulumtuese
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wetenschapper
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հետազոտող
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name
Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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Rosalie Matico
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0000-0003-2341-3767