The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells.
about
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent mannerPIKE-A is amplified in human cancers and prevents apoptosis by up-regulating AktA novel germline mutation of PTEN associated with brain tumours of multiple lineagesPTEN is a protein tyrosine phosphatase for IRS1The future role of personalized medicine in the treatment of glioblastoma multiformePTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7.MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol.Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor.Characterization of invading glioma cells using molecular analysis of leading-edge tissue.A novel human TPIP splice-variant (TPIP-C2) mRNA, expressed in human and mouse tissues, strongly inhibits cell growth in HeLa cells.PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling.Functional analysis of the protein phosphatase activity of PTENA new role for PTEN in regulating transient receptor potential canonical channel 6-mediated Ca2+ entry, endothelial permeability, and angiogenesis.Protein interactions of phosphatase and tensin homologue (PTEN) and its cancer-associated G20E mutant compared by using stable isotope labeling by amino acids in cell culture-based parallel affinity purification.PTEN induces apoptosis and cavitation via HIF-2-dependent Bnip3 upregulation during epithelial lumen formationAptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells.Negative regulation of CXCR4-mediated chemotaxis by the lipid phosphatase activity of tumor suppressor PTEN.The APC/C Ubiquitin Ligase: From Cell Biology to TumorigenesisTargeting prostate cancer based on signal transduction and cell cycle pathways.EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin.Glioblastoma Multiforme Oncogenomics and Signaling Pathways.PTEN dephosphorylates AKT to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cellsmTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma.Phosphatase and Tensin Homolog Is a Growth Repressor of Both Rhizoid and Gametophore Development in the Moss Physcomitrella patens.Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor.Phenotypic effects of overexpression of the MMAC1 gene in prostate epithelial cellsPTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complexPTEN: a promising pharmacological target to enhance epithelial wound healing.Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation.Nongenomic Mechanisms of PTEN Regulation.
P2860
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P2860
The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells.
@en
The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells.
@nl
type
label
The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells.
@en
The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells.
@nl
prefLabel
The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells.
@en
The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells.
@nl
P2093
P1433
P1476
The PTEN lipid phosphatase domain is not required to inhibit invasion of glioma cells
@en
P2093
P304
P407
P577
1999-11-01T00:00:00Z