mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma. - Wikidata - wikimedia - TriplyDB

mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma.

mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma.

http://www.wikidata.org/entity/Q40407116

about

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo Stem cell guidance through the mechanistic target of rapamycin A drosophila model for EGFR-Ras and PI3K-dependent human glioma Loss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era.A review of the past, present, and future directions of neoplasia Neoplasia: Where We Have Been and Where We Are Going Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma Interactions between PTEN and receptor tyrosine kinase pathways and their implications for glioma therapy Retinoblastoma loss modulates DNA damage response favoring tumor progression Oncogene interactions are required for glioma development and progression as revealed by a tissue specific transgenic mouse model Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells.The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas Activated MEK cooperates with Ink4a/Arf loss or Akt activation to induce gliomas in vivo Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation.Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma Experimental approaches for the treatment of malignant gliomas.mTOR signaling in glioblastoma: lessons learned from bench to bedside.R-RAS2 overexpression in tumors of the human central nervous system.North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme.Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells.Constitutive activation with overexpression of the mTORC2-phospholipase D1 pathway in uterine leiomyosarcoma and STUMP: morphoproteomic analysis with therapeutic implications.Anti-tumor effect of a novel PI3-kinase inhibitor, SF1126, in (12) V-Ha-Ras transgenic mouse glioma model.Prominin 1/CD133 endothelium sustains growth of proneural glioma.Glial progenitors as targets for transformation in glioma.A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors.Glaucocalyxin A, a negative Akt regulator, specifically induces apoptosis in human brain glioblastoma U87MG cells.Phase I study of temsirolimus in pediatric patients with recurrent/refractory solid tumors.Mesenchymal stem cells display tumor-specific tropism in an RCAS/Ntv-a glioma model Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.Drosophila melanogaster as a model system for human brain cancers.Insulin-like growth factor binding protein 2 promotes glioma development and progression The pro-survival pathways of mTOR and protein kinase B target glycogen synthase kinase-3beta and nuclear factor-kappaB to foster endogenous microglial cell protection.Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma.Identification of global alteration of translational regulation in glioma in vivo The sodium pump alpha1 subunit as a potential target to combat apoptosis-resistant glioblastomas.Fluorine-labeled dasatinib nanoformulations as targeted molecular imaging probes in a PDGFB-driven murine glioblastoma model.Platelet-derived growth factor receptor alpha in glioma: a bad seed Constitutive activation of Raf-1 induces glioma formation in mice.

P2860

Q24657924-FCB630A7-5590-4059-83F3-2D0DE056ECAA Q26795544-6BAD35A0-0818-4D5E-BBB1-C78DE53ADA96 Q27312887-6F039D5B-9EA7-4D24-ACF2-ED3A071A18AF Q27851755-9ED3F251-8BC3-4E18-8BF6-3F0DA02BC030 Q28389391-87BE044A-D657-4632-860A-5F2705D1681B Q28395095-2885ABE3-BF19-4C92-BBF6-CF789282C8FC Q28743461-56EB7233-630C-421E-8F1E-2316014562B6 Q30437740-32D5BDCF-CB57-4B72-9607-D9FD4B2A7C20 Q33382723-6C4C6F46-07B7-40D8-AAA2-CD9BCEC8C0AF Q33579323-F9153C12-D885-4AE1-B6F6-6E3BA55B975E Q33715154-C0B903AF-8C1E-4F2A-9B39-7EB48C4EFE65 Q33744491-5982CE08-7745-4DA9-9DE5-C480729FB2AC Q33945972-61668B42-0B5A-45F3-8E59-DFC6D6348794 Q33945989-C70ADFB7-2D93-4E97-8FE0-145518920339 Q33960280-27E31F72-0BED-4445-80F4-B55517110E64 Q34083282-C72BEE11-F260-4047-B9C4-B37EAA2D1EED Q34127138-B634DBC2-87E7-4670-9C84-DCED30EDC6F1 Q34133033-CA51E6C7-AACD-4981-9E33-1EB092689D23 Q34379469-DCAAE9AA-16B6-4715-8498-F44DE0762CBF Q34441838-A2C0B3C7-93B0-4438-AD00-B64C2DA26538 Q34480703-055672F1-D606-4019-9F39-E7B6CFADB5EB Q34566745-18921D65-4ABA-42F0-AD44-9D0B19F9B030 Q34568628-9EBE5DE7-4C34-4288-9DE8-5169F4682E7B Q34701002-C43DACDC-824B-4AEC-B4C2-1645130D353F Q34735661-24CE95D8-AE8B-400C-8CA3-EE5AE0204E10 Q34818301-15587D39-D95B-4528-9245-2EF7A6DC3F96 Q34991079-B5F42F57-7A68-43D0-A78B-0685294EE5A0 Q35112340-1692E3DA-D051-4339-9B4A-EFA9A4B217BC Q35166319-83D6FB71-15B9-4705-9718-499035C011AA Q35440540-B9D9D57B-1A7B-4F47-96FB-124B97E29833 Q35566228-98164FE2-8570-437E-8D65-28F16A7C36B7 Q35880328-32521CD6-B5F8-4D67-B7FF-315D23362EB2 Q36002875-8038CBE9-4421-42DE-AC43-6930C9AD9131 Q36100451-55D09B3B-584F-46B2-BC97-76E2FAC18FC2 Q36213745-27367D44-F2BA-4ABF-B5A6-A24C6849B7CB Q36295318-9F2BD376-6397-4C11-9551-1A48814C3812 Q36485266-A09B208C-80E9-40A2-9081-63C620291F88 Q36520705-E034361A-ED71-4176-8FC8-C1B29D79B11F Q36528159-303FC773-3C06-4B8D-8A89-042DE73864A4 Q36640215-5C24A2E9-6702-41C6-BA4A-610ABFCCB271

P2860

mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma.

http://www.wikidata.org/entity/Q40407116

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

2005年论文

@zh

2005年论文

@zh-cn

name

mTOR promotes survival and ast ...... AKT signaling in glioblastoma.

@en

type

label

mTOR promotes survival and ast ...... AKT signaling in glioblastoma.

@en

prefLabel

mTOR promotes survival and ast ...... AKT signaling in glioblastoma.

@en

P1433

Q40407116-BC38EA42-15F4-4275-AAE1-B446F90FB356

P1476

Q40407116-F5AC6647-A616-4FE9-B876-9AC9AC547E43

P2093

Q40407116-3A26C62D-A730-4389-8B6A-20C0859D7F71

Q40407116-4AD0B399-85DB-47DE-B48A-71A7A6138C80

Q40407116-4FBE2E63-BD75-428B-9B0B-FBCEFB4DF7CC

Q40407116-7477B224-0F19-42F8-9BD2-3C505DCAF17B

Q40407116-96CE5CFE-6008-4FCC-A4CF-571105D787CF

Q40407116-D3AB73C8-BAF5-49FC-9DAF-D620486FDABA

P2860

Q40407116-01ED4A0B-CB45-415F-9A34-D3AD056F5893

Q40407116-03228FB5-A034-4DA7-90E7-5C32BB46CAA1

Q40407116-049CC6C6-7E7F-4BBC-874F-D520C0FC9B93

Q40407116-077BCF46-A596-43BE-8266-CD10D4345C4F

Q40407116-0D93FA7E-67B1-49BC-81E3-54DACA7525C7

Q40407116-140C5D50-7599-4D4A-A348-B925F2FD9C35

Q40407116-14F25F21-E301-4C8C-86A9-43599272B5C8

Q40407116-187EC8D5-4046-46E4-951C-067AC8E1030B

Q40407116-19FA0983-EE27-498B-8009-795BC22E492A

Q40407116-1D73F62A-49A8-4BF5-BCF7-C52D5105DBD0

P304

Q40407116-7DE2391B-7767-4C95-8DEA-F228BE61535C

P31

Q40407116-3FF861CF-3D4D-4B67-9686-C73ECF3495EE

P356

Q40407116-3A99256C-3CFB-41A1-8F85-58E1B477BF0D

P433

Q40407116-ED037999-E3D3-4E99-B07A-0C69E20D2D1C

P478

Q40407116-3A195FA5-012A-4FAF-B980-286D251C1695

P577

Q40407116-37A169A9-1FB7-4175-894E-0FDFD9EEFD01

P5875

Q40407116-832B0267-1EC5-4FC9-805E-4B6D1B6C550C

P698

Q40407116-0F1F6EA3-F1D7-47A6-B1E8-B0447BB5DA64

P932

Q40407116-CFC30E16-EAB2-47B1-ACCC-5F1A11D4B448

P356

P1433

P1476

mTOR promotes survival and ast ...... AKT signaling in glioblastoma.

@en

P2093

Eric C Holland

http://www.w3.org/2001/XMLSchema#string

Jason A Koutcher

http://www.w3.org/2001/XMLSchema#string

Marc Rosenblum

http://www.w3.org/2001/XMLSchema#string

Pier Paolo Pandolfi

http://www.w3.org/2001/XMLSchema#string

Xiaoyi Hu

http://www.w3.org/2001/XMLSchema#string

Yi Li

http://www.w3.org/2001/XMLSchema#string

P2860

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

The PI3K-PDK1 connection: more than just a road to PKB

Cancerous stem cells can arise from pediatric brain tumors

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

Pten dose dictates cancer progression in the prostate

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

TOR, a central controller of cell growth.

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

P304

356-368

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1593/NEO.04595

http://www.w3.org/2001/XMLSchema#string

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P577

2005-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7776532

http://www.w3.org/2001/XMLSchema#string

P698

15967113

http://www.w3.org/2001/XMLSchema#string

P932

1501155

http://www.w3.org/2001/XMLSchema#string