about
Impact of enhancements in the local effect model (LEM) on the predicted RBE-weighted target dose distribution in carbon ion therapy.Assessment of potential advantages of relevant ions for particle therapy: a model based study.A model of photon cell killing based on the spatio-temporal clustering of DNA damage in higher order chromatin structures.Induction and Processing of the Radiation-Induced Gamma-H2AX Signal and Its Link to the Underlying Pattern of DSB: A Combined Experimental and Modelling Study.Direct measurement of the 3-dimensional DNA lesion distribution induced by energetic charged particles in a mouse model tissue.Kill-painting of hypoxic tumours in charged particle therapy.Comparative Risk Predictions of Second Cancers After Carbon-Ion Therapy Versus Proton TherapyOxygen beams for therapy: advanced biological treatment planning and experimental verification.A Comparison of Kinetic Photon Cell Survival Models.Sensitivity of the Giant LOop Binary LEsion (GLOBLE) cell survival model on parameters characterising dose rate effects.The link between cell-cycle dependent radiosensitivity and repair pathways: a model based on the local, sister-chromatid conformation dependent switch between NHEJ and HR.Modeling cell survival after irradiation with Ultrasoft X rays using the giant loop binary lesion model.Systematics of relative biological effectiveness measurements for proton radiation along the spread out Bragg peak: experimental validation of the local effect model.Physical and biological factors determining the effective proton range.New Insight into Quantitative Modeling of DNA Double-Strand Break Rejoining.Application of the local effect model to predict DNA double-strand break rejoining after photon and high-LET irradiation.Measuring Leukocyte Adhesion to (Primary) Endothelial Cells after Photon and Charged Particle Exposure with a Dedicated Laminar Flow Chamber.A DNA double-strand break kinetic rejoining model based on the local effect model.Quantification of the relative biological effectiveness for ion beam radiotherapy: direct experimental comparison of proton and carbon ion beams and a novel approach for treatment planning.Sensitivity analysis of the relative biological effectiveness predicted by the local effect model.Mapping of RBE-weighted doses between HIMAC- and LEM-Based treatment planning systems for carbon ion therapy.Quantum chaotic scattering in microwave resonators.Spectral fluctuations of billiards with mixed dynamics: from time series to superstatistics.Modeling Radiation Effects of Ultrasoft X Rays on the Basis of Amorphous Track Structure.Simulation of DSB yield for high LET radiation.Impact of fractionation and number of fields on dose homogeneity for intra-fractionally moving lung tumors using scanned carbon ion treatment.Friedel oscillations in microwave billiards.Integration of a model-independent interface for RBE predictions in a treatment planning system for active particle beam scanning.Relative biological effectiveness of carbon ions for tumor control, acute skin damage and late radiation-induced fibrosis in a mouse model.Response to the “Letter to the Editor” by K. H. Chadwick on our Article “A Comparison of Kinetic Photon Cell Survival Models”Comments on the paper “Modelling of cell killing due to sparsely ionizing radiation in normoxic and hypoxic conditions and an extension to high LET radiation” by A. Mairani et al., Int. J. Radiat. Biol. 89(10), 2013, 782–793RBE of ion beams in hypofractionated radiotherapy (SBRT)Particle species dependence of cell survival RBE: Evident and not negligibleCalculation of the biological effects of ion beams based on the microscopic spatial damage distribution patternDNA damage interactions on both nanometer and micrometer scale determine overall cellular damageNonperiodic echoes from quantum mushroom-billiard hatsInduced Violation of Time-Reversal Invariance in the Regime of Weakly Overlapping ResonancesChaotic scattering in the regime of weakly overlapping resonancesProperties of nodal domains in a pseudointegrable barrier billiardSpectral properties of Bunimovich mushroom billiards
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description
nuclear physicist at TU Darmstadt
@en
wetenschapper
@nl
name
T Friedrich
@nl
T Friedrich
@sl
Thomas Friedrich
@en
Thomas Friedrich
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type
label
T Friedrich
@nl
T Friedrich
@sl
Thomas Friedrich
@en
Thomas Friedrich
@es
prefLabel
T Friedrich
@nl
T Friedrich
@sl
Thomas Friedrich
@en
Thomas Friedrich
@es
P21
P31
P496
0000-0003-0074-6390