Calculation of the biological effects of ion beams based on the microscopic spatial damage distribution pattern
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Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET RadiationEffects of Charged Particles on Human Tumor CellsDNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choiceRandomized phase II trial of hypofractionated proton versus carbon ion radiation therapy in patients with sacrococcygeal chordoma-the ISAC trial protocol.Assessment of potential advantages of relevant ions for particle therapy: a model based study.Safety and Local Control of Radiation Therapy for Chordoma of the Spine and Sacrum: A Systematic Review.A model of photon cell killing based on the spatio-temporal clustering of DNA damage in higher order chromatin structures.The relative biological effectiveness for carbon and oxygen ion beams using the raster-scanning technique in hepatocellular carcinoma cell lines.Induction and Processing of the Radiation-Induced Gamma-H2AX Signal and Its Link to the Underlying Pattern of DSB: A Combined Experimental and Modelling Study.Genetic Analysis of T Cell Lymphomas in Carbon Ion-Irradiated Mice Reveals Frequent Interstitial Chromosome Deletions: Implications for Second Cancer Induction in Normal Tissues during Carbon Ion RadiotherapyDirect measurement of the 3-dimensional DNA lesion distribution induced by energetic charged particles in a mouse model tissue.Comparative Risk Predictions of Second Cancers After Carbon-Ion Therapy Versus Proton TherapyFeasibility Study on Cardiac Arrhythmia Ablation Using High-Energy Heavy Ion Beams.Efficient Rejoining of DNA Double-Strand Breaks despite Increased Cell-Killing Effectiveness following Spread-Out Bragg Peak Carbon-Ion Irradiation.A new formalism for modelling parameters α and β of the linear quadratic model of cell survival for hadron therapy.Radiobiological issues in proton therapy.Comprehensive track-structure based evaluation of DNA damage by light ions from radiotherapy-relevant energies down to stopping.Physical and biological factors determining the effective proton range.In vitro evaluation of photon and raster-scanned carbon ion radiotherapy in combination with gemcitabine in pancreatic cancer cell lines.Modelling of cell killing due to sparsely ionizing radiation in normoxic and hypoxic conditions and an extension to high LET radiation.Systematic analysis of RBE and related quantities using a database of cell survival experiments with ion beam irradiation.In vitro evaluation of photon and carbon ion radiotherapy in combination with chemotherapy in glioblastoma cells.Theoretical substantiation of biological efficacy enhancement for β-delayed particle decay (9)C beam: A Monte Carlo study in combination with analysis with the local effect model approach.Application of the local effect model to predict DNA double-strand break rejoining after photon and high-LET irradiation.Proton beam irradiation inhibits the migration of melanoma cells.Variable RBE in proton therapy: comparison of different model predictions and their influence on clinical-like scenarios.Impact of respiratory motion on variable relative biological effectiveness in 4D-dose distributions of proton therapy.Inclusion of a variable RBE into proton and photon plan comparison for various fractionation schedules in prostate radiation therapy.In Silico Non-Homologous End Joining Following Ion Induced DNA Double Strand Breaks Predicts That Repair Fidelity Depends on Break Density.New insights in the relative radiobiological effectiveness of proton irradiation.Simulation of DSB yield for high LET radiation.Comments on the paper “Modelling of cell killing due to sparsely ionizing radiation in normoxic and hypoxic conditions and an extension to high LET radiation” by A. Mairani et al., Int. J. Radiat. Biol. 89(10), 2013, 782–793DNA damage interactions on both nanometer and micrometer scale determine overall cellular damage
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Calculation of the biological effects of ion beams based on the microscopic spatial damage distribution pattern
description
im Oktober 2011 veröffentlichter wissenschaftlicher Artikel
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scientific article published on 05 October 2011
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wetenschappelijk artikel
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наукова стаття, опублікована в жовтні 2011
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name
Calculation of the biological ...... al damage distribution pattern
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Calculation of the biological ...... al damage distribution pattern
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type
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Calculation of the biological ...... al damage distribution pattern
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Calculation of the biological ...... al damage distribution pattern
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prefLabel
Calculation of the biological ...... al damage distribution pattern
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Calculation of the biological ...... al damage distribution pattern
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P2093
P2860
P1476
Calculation of the biological ...... al damage distribution pattern
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P2093
Michael Scholz
Thilo Elsässer
Uwe Scholz
P2860
P304
P356
10.3109/09553002.2011.611213
P577
2011-10-05T00:00:00Z