about
Interactions between calmodulin, adenosine A2A, and dopamine D2 receptorsIntegrated signaling in heterodimers and receptor mosaics of different types of GPCRs of the forebrain: relevance for schizophreniaIdentification of dopamine D1-D3 receptor heteromers. Indications for a role of synergistic D1-D3 receptor interactions in the striatumAdenosine A2A and dopamine D2 heteromeric receptor complexes and their functionAntagonistic cannabinoid CB1/dopamine D2 receptor interactions in striatal CB1/D2 heteromers. A combined neurochemical and behavioral analysisAdenosine A2A receptor and dopamine D3 receptor interactions: evidence of functional A2A/D3 heteromeric complexesThe human histamine H3 receptor couples to GIRK channels in Xenopus oocytesIncrease in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal.How calmodulin interacts with the adenosine A(2A) and the dopamine D(2) receptors.Cocaine produces D2R-mediated conformational changes in the adenosine A(2A)R-dopamine D2R heteromer.On the role of P2X(7) receptors in dopamine nerve cell degeneration in a rat model of Parkinson's disease: studies with the P2X(7) receptor antagonist A-438079.Rho-kinase inhibitor Y-27632 and hypoxia synergistically enhance chondrocytic phenotype and modify S100 protein profiles in human chondrosarcoma cells.Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaineMandelic acid condensation polymer: novel candidate microbicide for prevention of human immunodeficiency virus and herpes simplex virus entryFrom the Golgi-Cajal mapping to the transmitter-based characterization of the neuronal networks leading to two modes of brain communication: wiring and volume transmission.Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology.Chronic L-DOPA induces hyperactivity, normalization of gait and dyskinetic behavior in MitoPark miceAdenosine A2A-dopamine D2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders.A novel mechanism of cocaine to enhance dopamine d2-like receptor mediated neurochemical and behavioral effects. An in vivo and in vitro studyHerpes simplex virus triggers activation of calcium-signaling pathwaysIntramembrane receptor-receptor interactions: a novel principle in molecular medicine.Adenosine A(2A) receptors, dopamine D(2) receptors and their interactions in Parkinson's disease.Structural plasticity in G-protein coupled receptors as demonstrated by the allosteric actions of homocysteine and computer-assisted analysis of disordered domains.On the key role played by altered protein conformation in Parkinson's disease.Heterodimers and receptor mosaics of different types of G-protein-coupled receptors.Role of dopamine receptor mechanisms in the amygdaloid modulation of fear and anxiety: Structural and functional analysis.The discovery of central monoamine neurons gave volume transmission to the wired brain.Molecular integration via allosteric interactions in receptor heteromers. A working hypothesis.Adenosine-dopamine interactions in the pathophysiology and treatment of CNS disorders.Brain receptor mosaics and their intramembrane receptor-receptor interactions: molecular integration in transmission and novel targets for drug development.The changing world of G protein-coupled receptors: from monomers to dimers and receptor mosaics with allosteric receptor-receptor interactions.Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices.Dopamine D2 and 5-hydroxytryptamine 5-HT(₂A) receptors assemble into functionally interacting heteromers.Nanomolar concentrations of cocaine enhance D2-like agonist-induced inhibition of the K+-evoked [3H]-dopamine efflux from rat striatal synaptosomes: a novel action of cocaine.A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R.Galanin receptor-1 modulates 5-hydroxtryptamine-1A signaling via heterodimerization.Trafficking of adenosine A2A and dopamine D2 receptors.Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors.Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer.Pridopidine selectively occupies sigma-1 rather than dopamine D2 receptors at behaviorally active doses.
P50
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P50
description
researcher
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wetenschapper
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հետազոտող
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name
Daniel Marcellino
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Daniel Marcellino
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Daniel Marcellino
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Daniel Marcellino
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Daniel Marcellino
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type
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Daniel Marcellino
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Daniel Marcellino
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Daniel Marcellino
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Daniel Marcellino
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Daniel Marcellino
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D Marcellino
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Marcellino D
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Daniel Marcellino
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Daniel Marcellino
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Daniel Marcellino
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Daniel Marcellino
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Daniel Marcellino
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P108
P106
P1153
6603491077
P21
P31
P4012
P496
0000-0002-4618-7267