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Mild gestational diabetes in pregnancy and the adipoinsular axis in babies born to mothers in the ACHOIS randomised controlled trial.Hypothyroidism in utero stimulates pancreatic beta cell proliferation and hyperinsulinaemia in the ovine fetus during late gestation.Neonatal exendin-4 reduces growth, fat deposition and glucose tolerance during treatment in the intrauterine growth-restricted lamb.Developmental Expression and Glucocorticoid Control of the Leptin Receptor in Fetal Ovine Lung.Maternal Dexamethasone Treatment Alters Tissue and Circulating Components of the Renin-Angiotensin System in the Pregnant Ewe and Fetus.Effect of placental restriction and neonatal exendin-4 treatment on postnatal growth, adult body composition, and in vivo glucose metabolism in the sheep.Leptin Matures Aspects of Lung Structure and Function in the Ovine Fetus.Maternal and neonatal circulating markers of metabolic and cardiovascular risk in the metformin in gestational diabetes (MiG) trial: responses to maternal metformin versus insulin treatmentDeterminants of maternal triglycerides in women with gestational diabetes mellitus in the Metformin in Gestational Diabetes (MiG) study.Effects of induced placental and fetal growth restriction, size at birth and early neonatal growth on behavioural and brain structural lateralization in sheep.Insights into the role of maladaptive hexosamine biosynthesis and O-GlcNAcylation in development of diabetic cardiac complications.Phosphoinositide 3-kinase (p110α) gene delivery limits diabetes-induced cardiac NADPH oxidase and cardiomyopathy in a mouse model with established diastolic dysfunction.A physiological increase in maternal cortisol alters uteroplacental metabolism in the pregnant ewe.Placental restriction increases adipose leptin gene expression and plasma leptin and alters their relationship to feeding activity in the young lamb.Responses to maternal GH or ractopamine during early-mid pregnancy are similar in primiparous and multiparous pregnant pigs.Variable maternal nutrition and growth hormone treatment in the second quarter of pregnancy in pigs alter semitendinosus muscle in adolescent progeny.Postnatal ontogeny of glucose homeostasis and insulin action in sheep.Effect of variable long-term maternal feed allowance on the development of the ovine placenta and fetus.Improved lactational nutrition and postnatal growth ameliorates impairment of glucose tolerance by uteroplacental insufficiency in male rat offspring.Therapeutic targeting of oxidative stress with coenzyme Q10 counteracts exaggerated diabetic cardiomyopathy in a mouse model of diabetes with diminished PI3K(p110α) signaling.Small size at birth predicts decreased cardiomyocyte number in the adult ovine heart.Placental restriction of fetal growth reduces size at birth and alters postnatal growth, feeding activity, and adiposity in the young lamb.Placental and fetal growth restriction, size at birth and neonatal growth alter cognitive function and behaviour in sheep in an age- and sex-specific manner.Sex- and bone-specific responses in bone structure to exogenous leptin and leptin receptor antagonism in the ovine fetus.The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy.Placental restriction reduces insulin sensitivity and expression of insulin signaling and glucose transporter genes in skeletal muscle, but not liver, in young sheep.Sex-specific effects of placental restriction on components of the metabolic syndrome in young adult sheep.Placental restriction of fetal growth increases insulin action, growth, and adiposity in the young lamb.Placental restriction alters circulating thyroid hormone in the young lamb postnatally.Testing the plasticity of insulin secretion and β-cell functionin vivo: responses to chronic hyperglycaemia in the sheepMaternal responses to daily maternal porcine somatotropin injections during early-mid pregnancy or early-late pregnancy in sows and gilts1Impaired β-Cell Function and Inadequate Compensatory Increases in β-Cell Mass after Intrauterine Growth Restriction in SheepRestriction of placental growth in sheep impairs insulin secretion but not sensitivity before birthPerinatal growth and plasma GH profiles in adolescent and adult sheep
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P50
description
onderzoeker
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researcher
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հետազոտող
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Miles J De Blasio
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Miles J De Blasio
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Miles J De Blasio
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Miles J De Blasio
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Miles J De Blasio
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Miles J De Blasio
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Miles J De Blasio
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Miles De Blasio
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Miles J. De Blasio
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Miles J De Blasio
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Miles J De Blasio
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Miles J De Blasio
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Miles J De Blasio
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Miles J De Blasio
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P106
P31
P496
0000-0002-4797-5193