about
A family of thermostable fungal cellulases created by structure-guided recombinationSCHEMA recombination of a fungal cellulase uncovers a single mutation that contributes markedly to stabilityStructure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanolGeneral approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADHStructure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and SerotoninComparison of random mutagenesis and semi-rational designed libraries for improved cytochrome P450 BM3-catalyzed hydroxylation of small alkanesEvolutionary history of a specialized p450 propane monooxygenaseSide-chain recognition and gating in the ribosome exit tunnel.A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments.Non-bulk-like solvent behavior in the ribosome exit tunnel.Dimerization of the p53 oligomerization domain: identification of a folding nucleus by molecular dynamics simulations.How well can simulation predict protein folding kinetics and thermodynamics?A diverse set of family 48 bacterial glycoside hydrolase cellulases created by structure-guided recombination.Combinatorial alanine substitution enables rapid optimization of cytochrome P450BM3 for selective hydroxylation of large substrates.Characterization of the target of ivermectin, the glutamate-gated chloride channel, from Anopheles gambiae.Discriminating between stabilizing and destabilizing protein design mutations via recombination and simulation.Conservative and compensatory evolution in oxidative phosphorylation complexes of angiosperms with highly divergent rates of mitochondrial genome evolution.Trp zipper folding kinetics by molecular dynamics and temperature-jump spectroscopy.Polarizable protein packing.Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli.Kinetic definition of protein folding transition state ensembles and reaction coordinatesElectric fields at the active site of an enzyme: direct comparison of experiment with theory.Molecular dynamics simulations of cellulase homologs in aqueous 1-ethyl-3-methylimidazolium chloride.Installing Guest Molecules at Specific Sites within Scaffold Protein Crystals.Protein crystal based materials for nanoscale applications in medicine and biotechnologyPorous protein crystals as scaffolds for enzyme immobilizationPorous crystals as scaffolds for structural biologyAdvancing biomarkers for anaerobic o-xylene biodegradation via metagenomic analysis of a methanogenic consortium
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Christopher D Snow
@ast
Christopher D Snow
@en
Christopher D Snow
@es
Christopher D Snow
@nl
Christopher D Snow
@sl
type
label
Christopher D Snow
@ast
Christopher D Snow
@en
Christopher D Snow
@es
Christopher D Snow
@nl
Christopher D Snow
@sl
prefLabel
Christopher D Snow
@ast
Christopher D Snow
@en
Christopher D Snow
@es
Christopher D Snow
@nl
Christopher D Snow
@sl
P106
P21
P31
P496
0000-0002-7690-3519