about
Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humansLactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoASIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylaseIncreased palmitate intake: higher acylcarnitine concentrations without impaired progression of β-oxidation.Comprehensive metabolic modeling of multiple 13C-isotopomer data sets to study metabolism in perfused working hearts.Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs.Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice.A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growthDownregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction.Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individualsAdipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesisLipid partitioning, incomplete fatty acid oxidation, and insulin signal transduction in primary human muscle cells: effects of severe obesity, fatty acid incubation, and fatty acid translocase/CD36 overexpressionMetabolism and vascular fatty acid transport.Metabolic profiling of muscle contraction in lean compared with obese rodents.Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness.Genome-wide chromatin state transitions associated with developmental and environmental cues.Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in moodDownregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretionShort-term effects of dietary fatty acids on muscle lipid composition and serum acylcarnitine profile in human subjects.Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach.A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals.Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes.Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy.Compartmentalized acyl-CoA metabolism in skeletal muscle regulates systemic glucose homeostasisPeripheral metabolic actions of leptin.Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system.Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection.Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric RestrictionMetabolomic analysis reveals altered skeletal muscle amino acid and fatty acid handling in obese humans.Intramuscular triacylglycerol and insulin resistance: guilty as charged or wrongly accused?Diabetes: The good in fat.Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2.ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease PathogenesisLipid-induced mitochondrial stress and insulin action in muscleMuscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibilityHarnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative.Obesity-related derangements in metabolic regulation.Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue during ExerciseThe Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-Induced Lysine Acetylation of Mitochondrial Proteins
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Deborah M Muoio
@ast
Deborah M Muoio
@en
Deborah M Muoio
@es
Deborah M Muoio
@nl
Deborah M Muoio
@sl
type
label
Deborah M Muoio
@ast
Deborah M Muoio
@en
Deborah M Muoio
@es
Deborah M Muoio
@nl
Deborah M Muoio
@sl
prefLabel
Deborah M Muoio
@ast
Deborah M Muoio
@en
Deborah M Muoio
@es
Deborah M Muoio
@nl
Deborah M Muoio
@sl
P106
P1153
6602130092
P21
P31
P496
0000-0003-3760-9277