about
Quantification of Cre-mediated recombination by a novel strategy reveals a stable extra-chromosomal deletion-circle in mice.Rapid high-throughput analysis of DNaseI hypersensitive sites using a modified Multiplex Ligation-dependent Probe Amplification approachUrine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression.Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney DiseaseDose-dependent effects of sirolimus on mTOR signaling and polycystic kidney diseaseVariable Cyst Development in Autosomal Dominant Polycystic Kidney Disease: The Biologic Context.Meta-analysis of polycystic kidney disease expression profiles defines strong involvement of injury repair processes.Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.STAT5 drives abnormal proliferation in autosomal dominant polycystic kidney disease.Proteomics of Urinary Vesicles Links Plakins and Complement to Polycystic Kidney Disease.Fluid shear stress-induced TGF-β/ALK5 signaling in renal epithelial cells is modulated by MEK1/2.Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model.Transgenic mice expressing tamoxifen-inducible Cre for somatic gene modification in renal epithelial cells.Altered Hippo signalling in polycystic kidney disease.High-Throughput Phenotypic Screening of Kinase Inhibitors to Identify Drug Targets for Polycystic Kidney DiseaseLowering of Pkd1 expression is sufficient to cause polycystic kidney diseaseCommon regulatory elements in the polycystic kidney disease 1 and 2 promoter regionsElevated TGFbeta-Smad signalling in experimental Pkd1 models and human patients with polycystic kidney diseaseCyst expansion and regression in a mouse model of polycystic kidney disease
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Wouter N Leonhard
@ast
Wouter N Leonhard
@en
Wouter N Leonhard
@es
Wouter N Leonhard
@nl
type
label
Wouter N Leonhard
@ast
Wouter N Leonhard
@en
Wouter N Leonhard
@es
Wouter N Leonhard
@nl
prefLabel
Wouter N Leonhard
@ast
Wouter N Leonhard
@en
Wouter N Leonhard
@es
Wouter N Leonhard
@nl
P106
P1153
7003995193
P31
P496
0000-0002-6286-4424