Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model.
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Regulation of STATs by polycystin-1 and their role in polycystic kidney diseaseExperimental therapies and ongoing clinical trials to slow down progression of ADPKDThe role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologiesEffects of TORC1 Inhibition during the Early and Established Phases of Polycystic Kidney DiseaseGenetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease.The cleaved cytoplasmic tail of polycystin-1 regulates Src-dependent STAT3 activation.Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathwaysPyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease.Inactivation of integrin-β1 prevents the development of polycystic kidney disease after the loss of polycystin-1.Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression.Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney DiseaseDiscovery of curcumin, a component of golden spice, and its miraculous biological activities.Dose-dependent effects of sirolimus on mTOR signaling and polycystic kidney diseaseVasopressin and disruption of calcium signalling in polycystic kidney disease.Ginkgolide B inhibits renal cyst development in in vitro and in vivo cyst models.STAT3 Signaling in Polycystic Kidney DiseaseAndrogen-STAT3 activation may contribute to gender disparity in human simply renal cystsAutocrine IL-10 activation of the STAT3 pathway is required for pathological macrophage differentiation in polycystic kidney diseasePolycystic kidney disease in 2011: Connecting the dots toward a polycystic kidney disease therapy.Hitting the golden TORget: curcumin's effects on mTOR signaling.Multidrug therapy for polycystic kidney disease: a review and perspective.New treatments for autosomal dominant polycystic kidney diseaseEvidence for a role of proteins, lipids, and phytochemicals in the prevention of polycystic kidney disease progression and severity.Strategies targeting cAMP signaling in the treatment of polycystic kidney disease.JAK inhibition and progressive kidney disease.Polycystin-1 regulates amphiregulin expression through CREB and AP1 signalling: implications in ADPKD cell proliferation.Nephronophthisis: should we target cysts or fibrosis?Clinical Trials in Pediatric Autosomal Dominant Polycystic Kidney Disease.Clinical Trials and a View Toward the Future of ADPKD.Variable Cyst Development in Autosomal Dominant Polycystic Kidney Disease: The Biologic Context.Combination drug versus monotherapy for the treatment of autosomal dominant polycystic kidney disease.Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.Src family kinases in chronic kidney disease.Proteomics of Urinary Vesicles Links Plakins and Complement to Polycystic Kidney Disease.Fluid shear stress-induced TGF-β/ALK5 signaling in renal epithelial cells is modulated by MEK1/2.Comprehensive transcriptome analysis of fluid shear stress altered gene expression in renal epithelial cells.Stat3 Controls Tubulointerstitial Communication during CKD.Identification of Targets of Interleukin-13 and Signal Transducer and Activator of Transcription-6 (STAT6) Signaling in Polycystic Kidney Disease.Parallel microarray profiling identifies ErbB4 as a determinant of cyst growth in ADPKD and a prognostic biomarker for disease progression.Double inhibition of cAMP and mTOR signalling may potentiate the reduction of cell growth in ADPKD cells.
P2860
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P2860
Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Curcumin inhibits cystogenesis ...... ce from a Pkd1-deletion model.
@en
Curcumin inhibits cystogenesis ...... ce from a Pkd1-deletion model.
@nl
type
label
Curcumin inhibits cystogenesis ...... ce from a Pkd1-deletion model.
@en
Curcumin inhibits cystogenesis ...... ce from a Pkd1-deletion model.
@nl
prefLabel
Curcumin inhibits cystogenesis ...... ce from a Pkd1-deletion model.
@en
Curcumin inhibits cystogenesis ...... ce from a Pkd1-deletion model.
@nl
P2093
P1476
Curcumin inhibits cystogenesis ...... nce from a Pkd1-deletion model
@en
P2093
Annemieke van der Wal
Dorien J M Peters
Emile de Heer
Martijn H Breuning
Ron T Gansevoort
Zlata Novalic
P304
P356
10.1152/AJPRENAL.00419.2010
P577
2011-02-23T00:00:00Z