about
Retrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and diseaseCorticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 FunctionAAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS.Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanismsHealthy and diseased corticospinal motor neurons are selectively transduced upon direct AAV2-2 injection into the motor cortex.Could dysregulation of UPS be a common underlying mechanism for cancer and neurodegeneration? Lessons from UCHL1.Tumor necrosis factor alpha stimulates NMDA receptor activity in mouse cortical neurons resulting in ERK-dependent death.
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Q26823894-E32668CF-6BE7-4EC3-82FC-7723CE2D2744Q27302932-634B909B-95FF-4BD5-A6B9-D5172A721A50Q33726831-4FE75D13-1990-4C7A-A049-6CA8863429A2Q36608848-D8667B3C-F3A2-4941-9462-49BB1D4832BBQ36649800-7B2B4EBD-6E79-477F-8477-6E69A0EFCCFCQ38108538-7E299116-BD49-4D32-82FA-9B410118D41FQ39668898-F29D1665-C265-4630-A199-FEEB423D8E24
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Javier H Jara
@ast
Javier H Jara
@en
Javier H Jara
@es
Javier H Jara
@nl
type
label
Javier H Jara
@ast
Javier H Jara
@en
Javier H Jara
@es
Javier H Jara
@nl
prefLabel
Javier H Jara
@ast
Javier H Jara
@en
Javier H Jara
@es
Javier H Jara
@nl
P108
P106
P1153
15845404500
P31
P496
0000-0002-6722-2834