about
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotidesSequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G{middle dot}C{middle dot}G{middle dot}C tetradRe-evaluation of G-quadruplex propensity with G4HunterAnalysis of thermal melting curves.DNA nanomachines and nanostructures involving quadruplexes.Guanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes.Fluorescence-based melting assays for studying quadruplex ligands.8-Amino guanine accelerates tetramolecular G-quadruplex formation.G-Quadruplex formation interferes with P1 helix formation in the RNA component of telomerase hTERC.Targeting human telomerase for cancer therapeutics.Chromatin immunoprecipitation indirect peaks highlight long-range interactions of insulator proteins and Pol II pausing.Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of actionTelomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.Selective interaction of ethidium derivatives with quadruplexes: an equilibrium dialysis and electrospray ionization mass spectrometry analysis.Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors.Triple helix formation with Drosophila satellite repeats. Unexpected stabilization by copper ions.Targeting telomeres and telomeraseA Metal-Mediated Conformational Switch Controls G-Quadruplex Binding AffinityQuadruplex-based molecular beacons as tunable DNA probesTelomerase: a dimeric ménage à trois
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Laurent Lacroix
@ast
Laurent Lacroix
@en
Laurent Lacroix
@es
Laurent Lacroix
@nl
type
label
Laurent Lacroix
@ast
Laurent Lacroix
@en
Laurent Lacroix
@es
Laurent Lacroix
@nl
prefLabel
Laurent Lacroix
@ast
Laurent Lacroix
@en
Laurent Lacroix
@es
Laurent Lacroix
@nl
P106
P31
P496
0000-0002-6382-9057