Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis
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Toxic epidermal necrolysis and Stevens-Johnson syndromeBiology and clinical relevance of granulysinDrug induced exfoliative dermatitis: state of the artToxic epidermal necrolysisT-cell-mediated drug hypersensitivity: immune mechanisms and their clinical relevanceMucosal-associated invariant T cells from induced pluripotent stem cells: A novel approach for modeling human diseasesReport from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.New approaches for predicting T cell-mediated drug reactions: A role for inducible and potentially preventable autoimmunityEvolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response.Idiosyncratic adverse drug reactions: current conceptsReview of Toxic Epidermal NecrolysisSevere Cutaneous Adverse Reactions: The Pharmacogenomics from Research to Clinical ImplementationCytotoxic proteins and therapeutic targets in severe cutaneous adverse reactionsRecovered patients with Stevens-Johson syndrome and toxic epidermal necrolysis maintain long-lived IFN-γ and sFasL memory responseABC transporters and the proteasome complex are implicated in susceptibility to Stevens-Johnson syndrome and toxic epidermal necrolysis across multiple drugsAntimicrobial Properties of an Immunomodulator - 15 kDa Human GranulysinWhat Taiwan contributes to the world of allergy and clinical immunology?A Review on Dapsone Hypersensitivity Syndrome Among Chinese Patients with an Emphasis on Preventing Adverse Drug Reactions with Genetic TestingHLA associations and clinical implications in T-cell mediated drug hypersensitivity reactions: an updated review.Drug Hypersensitivity and Desensitizations: Mechanisms and New ApproachesStevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures.Pharmacogenetics of drug hypersensitivity.The current understanding of Stevens-Johnson syndrome and toxic epidermal necrolysis.Oral acetazolamide after Boston keratoprosthesis in Stevens-Johnson syndrome.Expression and purification of 15 kDa granulysin utilizing an insect cell secretion system.Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.Lamotrigine-induced toxic epidermal necrolysis confirmed by in vitro granulysin and cytokine assays.Severe cutaneous adverse drug reactions.Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.Drug hypersensitivity: pharmacogenetics and clinical syndromes.Novel gene expression responses in the ovine abomasal mucosa to infection with the gastric nematode Teladorsagia circumcincta.PharmGKB summary: very important pharmacogene information for human leukocyte antigen B.Cell death mechanisms at the maternal-fetal interface: insights into the role of granulysin.15 kDa granulysin causes differentiation of monocytes to dendritic cells but lacks cytotoxic activity.In vivo potential of recombinant granulysin against human tumors.The Effect of Intravenous Immunoglobulin Combined with Corticosteroid on the Progression of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Meta-Analysis.Bibliometric analysis of literature on toxic epidermal necrolysis and Stevens-Johnson syndrome: 1940 - 2015Systemic Immunomodulating Therapies for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review and Meta-analysis.EMPACT syndrome: limited evidence despite a high-risk cohort.Testing for drug hypersensitivity syndromes.
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Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis
description
article
@en
im November 2008 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
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наукова стаття, опублікована в листопаді 2008
@uk
ലേഖനം
@ml
name
Granulysin is a key mediator f ...... and toxic epidermal necrolysis
@en
Granulysin is a key mediator f ...... and toxic epidermal necrolysis
@nl
type
label
Granulysin is a key mediator f ...... and toxic epidermal necrolysis
@en
Granulysin is a key mediator f ...... and toxic epidermal necrolysis
@nl
prefLabel
Granulysin is a key mediator f ...... and toxic epidermal necrolysis
@en
Granulysin is a key mediator f ...... and toxic epidermal necrolysis
@nl
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P2860
P356
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P1476
Granulysin is a key mediator f ...... and toxic epidermal necrolysis
@en
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Chi-Fang Lu
Chien-Chun Chiou
Chih-Hsun Yang
Chun-Yu Wei
Hsin-Chun Ho
Jer-Yuarn Wu
Jui-Yung Yang
See-Wen Chin
Shien-Ping Huang
Shih-Chi Su
P2860
P2888
P304
P356
10.1038/NM.1884
P407
P577
2008-11-23T00:00:00Z
P5875
P6179
1048443479