about
Dendritic cells in lung immunopathologyCD4+CD25+ regulatory cells contribute to the regulation of colonic Th2 granulomatous pathology caused by schistosome infectionFluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cellsCD11c depletion severely disrupts Th2 induction and development in vivo.A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection.Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype.Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells.Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation.CD4+ T cell hyporesponsiveness after repeated exposure to Schistosoma mansoni larvae is dependent upon interleukin-10.A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivoModulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid.Plasma membrane proteomes of differentially matured dendritic cells identified by LC-MS/MS combined with iTRAQ labelling.A central role for hepatic conventional dendritic cells in supporting Th2 responses during helminth infectionGenetic diversity in Cypripedium calceolus (Orchidaceae) with a focus on north-western Europe, as revealed by plastid DNA length polymorphismsType I interferon is required for T helper (Th) 2 induction by dendritic cells.Diminished airway macrophage expression of the Axl receptor tyrosine kinase is associated with defective efferocytosis in asthma.Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration.A non-myeloablative chimeric mouse model accurately defines microglia and macrophage contribution in glioma.Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ production.Dynamics of Colon Monocyte and Macrophage Activation During ColitisThe major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 functionThe lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammationThe Methyl-CpG-Binding Protein Mbd2 Regulates Susceptibility to Experimental Colitis via Control of CD11c+ Cells and Colonic EpitheliumMacrophages assemble! But do they need IL-4R during schistosomiasis?The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Peter C Cook
@ast
Peter C Cook
@en
Peter C Cook
@es
Peter C Cook
@nl
type
label
Peter C Cook
@ast
Peter C Cook
@en
Peter C Cook
@es
Peter C Cook
@nl
prefLabel
Peter C Cook
@ast
Peter C Cook
@en
Peter C Cook
@es
Peter C Cook
@nl
P106
P1153
35147706600
P31
P496
0000-0002-5208-4985