A Simple and Modular Strategy for Small Molecule Synthesis: Iterative Suzuki−Miyaura Coupling of B-Protected Haloboronic Acid Building Blocks
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Simple, efficient, and modular syntheses of polyene natural products via iterative cross-couplingBioinspired iterative synthesis of polyketidesOxidation of organotrifluoroborates via oxonePalladium-catalyzed Suzuki-Miyaura cross-coupling reactions employing dialkylbiaryl phosphine ligands.Organotrifluoroborates and monocoordinated palladium complexes as catalysts--a perfect combination for Suzuki-Miyaura coupling.Replacing conventional carbon nucleophiles with electrophiles: nickel-catalyzed reductive alkylation of aryl bromides and chloridesFunctionalized olefin cross-coupling to construct carbon-carbon bonds.A method for the deprotection of alkylpinacolyl boronate esters.Oxidative Heck Reactions using Aryltrifluoroborates and Aryl N-Methyliminodiacetic Acid (MIDA) BoronatesReversible click reactions with boronic acids to build supramolecular architectures in water.Ru-catalysed C-H arylation of indoles and pyrroles with boronic acids: scope and mechanistic studiesBoryl (Hetero)aryne Precursors as Versatile Arylation Reagents: Synthesis through C-H Activation and Orthogonal Reactivity.Protecting group-free, selective cross-coupling of alkyltrifluoroborates with borylated aryl bromides via photoredox/nickel dual catalysis.Amphotericin primarily kills yeast by simply binding ergosterol.Near-IR BODIPY Dyes à la Carte-Programmed Orthogonal Functionalization of Rationally Designed Building Blocks.From synthesis to function via iterative assembly of N-methyliminodiacetic acid boronate building blocks.Stereocontrolled Synthesis of Vinyl Boronates and Vinyl Silanes via Atom-Economical Ruthenium-Catalyzed Alkene-Alkyne Coupling.Stereoselective synthesis of dienyl-carboxylate building blocks: formal synthesis of inthomycin C.Electrophilic C-H Borylation and Related Reactions of B-H Boron CationsThe Pyridyldiisopropylsilyl Group: A Masked Functionality and Directing Group for Monoselective ortho-Acyloxylation and ortho-Halogenation Reactions of Arenes.DABO Boronates: Stable Heterocyclic Boronic Acid Complexes for Use in Suzuki-Miyaura Cross-Coupling Reactions.MIDA boronates are hydrolysed fast and slow by two different mechanisms.A Divalent Protecting Group for Benzoxaboroles.Development of a Suzuki cross-coupling reaction between 2-azidoarylboronic pinacolate esters and vinyl triflates to enable the synthesis of [2,3]-fused indole heterocycles.Selection of boron reagents for Suzuki-Miyaura coupling.Pinene-derived iminodiacetic acid (PIDA): a powerful ligand for stereoselective synthesis and iterative cross-coupling of C(sp3) boronate building blocks.Linchpin dienes: key building-blocks in the synthesis of polyenic frameworks.Sequential and iterative Pd-catalyzed cross-coupling reactions in organic synthesis.Ligand-accelerated cross-coupling of C(sp2)-H bonds with arylboron reagents.Iterative protecting group-free cross-coupling leading to chiral multiply arylated structures.Cross-electrophile coupling: principles of reactivity and selectivityEnantioselective, organocatalytic oxy-michael addition to gamma/delta-hydroxy-alpha,beta-enones: boronate-amine complexes as chiral hydroxide synthons.Chemoselective boronic ester synthesis by controlled speciation.3-Cyanoallyl boronates are versatile building blocks in the synthesis of polysubstituted thiophenes.Palladium-catalysed cross-coupling reaction of ultra-stabilised 2-aryl-1,3-dihydro-1H-benzo[d]1,3,2-diazaborole compounds with aryl bromides: A direct protocol for the preparation of unsymmetrical biaryls.A general strategy toward aromatic 1,2-ambiphilic synthons: palladium-catalyzed ortho-halogenation of PyDipSi-arenesTotal synthesis of synechoxanthin through iterative cross-coupling.Synthesis of most polyene natural product motifs using just 12 building blocks and one coupling reaction.Synthesis of many different types of organic small molecules using one automated process.Iterative Cross-Couplng with MIDA Boronates: Towards a General Platform for Small Molecule Synthesis.
P2860
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P2860
A Simple and Modular Strategy for Small Molecule Synthesis: Iterative Suzuki−Miyaura Coupling of B-Protected Haloboronic Acid Building Blocks
description
im Mai 2007 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в травні 2007
@uk
name
A Simple and Modular Strategy ...... loboronic Acid Building Blocks
@en
A Simple and Modular Strategy ...... loboronic Acid Building Blocks
@nl
type
label
A Simple and Modular Strategy ...... loboronic Acid Building Blocks
@en
A Simple and Modular Strategy ...... loboronic Acid Building Blocks
@nl
prefLabel
A Simple and Modular Strategy ...... loboronic Acid Building Blocks
@en
A Simple and Modular Strategy ...... loboronic Acid Building Blocks
@nl
P356
P1476
A Simple and Modular Strategy ...... loboronic Acid Building Blocks
@en
P2093
Eric P. Gillis
Martin D. Burke
P304
P356
10.1021/JA0716204
P407
P577
2007-05-01T00:00:00Z