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MBD4 interacts with and recruits USP7 to heterochromatic fociDifferential expression of prognostic proteomic markers in primary tumour, venous tumour thrombus and metastatic renal cell cancer tissue and correlation with patient outcomeMatrix-free mass spectrometric imaging using laser desorption ionisation Fourier transform ion cyclotron resonance mass spectrometry.TMA Navigator: Network inference, patient stratification and survival analysis with tissue microarray dataA gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of SykA model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen.Quantification of tumour budding, lymphatic vessel density and invasion through image analysis in colorectal cancerNovel Monte Carlo approach quantifies data assemblage utility and reveals power of integrating molecular and clinical information for cancer prognosisTGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21Cip1 or Rb status.Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humansChemotherapy-induced dynamic gene expression changes in vivo are prognostic in ovarian cancer.Sprouty 2 is an independent prognostic factor in breast cancer and may be useful in stratifying patients for trastuzumab therapyDynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer.Diversity of matriptase expression level and function in breast cancer.Conductive carbon tape used for support and mounting of both whole animal and fragile heat-treated tissue sections for MALDI MS imaging and quantitation.MBD1, MBD2 and CGBP genes at chromosome 18q21 are infrequently mutated in human colon and lung cancers.Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer.While K-ras is essential for mouse development, expression of the K-ras 4A splice variant is dispensable.Increased STAT1 signaling in endocrine-resistant breast cancer.Long-term culture of human breast cancer specimens and their analysis using optical projection tomography.Carbonic anhydrase 9 expression increases with vascular endothelial growth factor-targeted therapy and is predictive of outcome in metastatic clear cell renal cancer.Transplant histopathology for the general histopathologist.Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model systemMulti-Scale Genomic, Transcriptomic and Proteomic Analysis of Colorectal Cancer Cell Lines to Identify Novel BiomarkersDynamic modulation of phosphoprotein expression in ovarian cancer xenograft modelsDefining the molecular response to trastuzumab, pertuzumab and combination therapy in ovarian cancer.Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression.A signaling visualization toolkit to support rational design of combination therapies and biomarker discovery: SiViT.Gene therapy for chronic obstructive pulmonary disease: twilight or triumph?Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network.Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002.Targeting of Rac GTPases blocks the spread of intact human breast cancer.Tissue of origin determines cancer-associated CpG island promoter hypermethylation patternsCharacterising the tumour morphological response to therapeutic intervention: an ex vivo model.Mitochondrial D-loop mutations and deletion profiles of cancerous and noncancerous liver tissue in hepatitis B virus-infected liverGenetic and epigenetic analyses of MBD3 in colon and lung cancer.The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer.Antitumour activity of the novel flavonoid Oncamex in preclinical breast cancer models.Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies.A novel mechanism of action of HER2 targeted immunotherapy is explained by inhibition of NRF2 function in ovarian cancer cells.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
David J Harrison
@ast
David J Harrison
@en
David J Harrison
@es
David J Harrison
@nl
type
label
David J Harrison
@ast
David J Harrison
@en
David J Harrison
@es
David J Harrison
@nl
prefLabel
David J Harrison
@ast
David J Harrison
@en
David J Harrison
@es
David J Harrison
@nl
P108
P106
P21
P31
P496
0000-0001-9041-9988