about
Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell SubsetsIntracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-PresentationIRAP identifies an endosomal compartment required for MHC class I cross-presentationER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cellsA detailed analysis of the murine TAP transporter substrate specificityBeyond the proteasome: trimming, degradation and generation of MHC class I ligands by auxiliary proteases.Differential proteasomal processing of hydrophobic and hydrophilic protein regions: contribution to cytotoxic T lymphocyte epitope clustering in HIV-1-Nef.A proteasome-dependent, TAP-independent pathway for cross-presentation of phagocytosed antigen.Pancreatic β-Cells Limit Autoimmune Diabetes via an Immunoregulatory Antimicrobial Peptide Expressed under the Influence of the Gut Microbiota.Complexity, contradictions, and conundrums: studying post-proteasomal proteolysis in HLA class I antigen presentation.Insulin-regulated aminopeptidase and its compartment in dendritic cells.IRAP+ endosomes restrict TLR9 activation and signaling.Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues.A long N-terminal-extended nested set of abundant and antigenic major histocompatibility complex class I natural ligands from HIV envelope protein.Novel selective inhibitors of aminopeptidases that generate antigenic peptides.ERAP1-ERAP2 dimerization increases peptide-trimming efficiency.Powering the peptide pump: TAP crosstalk with energetic nucleotides.Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.Ex vivo characterization of multiepitopic tumor-specific CD8 T cells in patients with chronic myeloid leukemia: implications for vaccine development and adoptive cellular immunotherapy.New pieces in the complex puzzle of aberrant vacuolation. Focus on "Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency".The Isoform Selective Roles of PI3Ks in Dendritic Cell Biology and FunctionRegulation of transporters associated with antigen processing (TAPs) by nucleotide binding to, and hydrolysis by, Walker consensus sequencesThe role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentationDendritic cells: open for presentation businessConventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentationPreparing antigens suitable for cross-presentation assays in vitro and in vivoImpact of the TAP-like transporter in antigen presentation and phagosome maturationInnate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-PresentationLC3-associated phagocytosis protects against inflammation and liver fibrosis via immunoreceptor inhibitory signalingIRAP-dependent endosomal T cell receptor signalling is essential for T cell responses
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P50
description
researcher
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wetenschapper
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հետազոտող
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name
Loredana Saveanu
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Loredana Saveanu
@en
Loredana Saveanu
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Loredana Saveanu
@nl
type
label
Loredana Saveanu
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Loredana Saveanu
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Loredana Saveanu
@es
Loredana Saveanu
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prefLabel
Loredana Saveanu
@ast
Loredana Saveanu
@en
Loredana Saveanu
@es
Loredana Saveanu
@nl
P106
P31
P496
0000-0003-3138-7968