IRAP identifies an endosomal compartment required for MHC class I cross-presentation
about
Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell SubsetsIntracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-PresentationCross-presentation of IgG-containing immune complexesThe Role of FcRn in Antigen PresentationMechanisms of HIV protein degradation into epitopes: implications for vaccine designAntigenic peptide trimming by ER aminopeptidases--insights from structural studiesA Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen ProcessingRationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responsesAntigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune DiseasesDifferent cross-presentation pathways in steady-state and inflammatory dendritic cellsA genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathyInsulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesiclesPathways of antigen processing.Key Features of Gamma-Delta T-Cell Subsets in Human Diseases and Their Immunotherapeutic Implications.Prolonged antigen survival and cytosolic export in cross-presenting human gammadelta T cellsPlacental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1Analysis of phagosomal proteomes: from latex-bead to bacterial phagosomesCrystallization and preliminary X-ray diffraction analysis of human endoplasmic reticulum aminopeptidase 2.Proteases in MHC class I presentation and cross-presentationIdentification and development of specific inhibitors for insulin-regulated aminopeptidase as a new class of cognitive enhancers.Endoplasmic reticulum aminopeptidase 1 and rheumatic disease: functional variation.CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease.Antigen processing and remodeling of the endosomal pathway: requirements for antigen cross-presentation.The role of insulin-regulated aminopeptidase in MHC class I antigen presentation.Immunoglobulins drive terminal maturation of splenic dendritic cells.Robust T-cell stimulation by Epstein-Barr virus-transformed B cells after antigen targeting to DEC-205.PD1-based DNA vaccine amplifies HIV-1 GAG-specific CD8+ T cells in miceDistinct Transcriptional Programs Control Cross-Priming in Classical and Monocyte-Derived Dendritic CellsScreening Identifies Thimerosal as a Selective Inhibitor of Endoplasmic Reticulum Aminopeptidase 1.A PCR-RFLP method for detection of the LNPEP encoding human insulin-regulated aminopeptidase (IRAP) rs4869317 polymorphism.Increased translocation of antigens to endosomes and TLR4 mediated endosomal recruitment of TAP contribute to nicotine augmented cross-presentation.Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides.Designing CD8+ T cell vaccines: it's not rocket science (yet).Providing ligands for MHC class I molecules.Post-proteasomal and proteasome-independent generation of MHC class I ligands.Antigen cross-presentation: extending recent laboratory findings to therapeutic intervention.Running the gauntlet: from peptide generation to antigen presentation by MHC class I.A modular and combinatorial view of the antigen cross-presentation pathway in dendritic cells.Cross-presentation: how to get there - or how to get the ER.Into the intracellular logistics of cross-presentation.
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P2860
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
description
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2009
@ast
im Juli 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/07/10)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/07/10)
@nl
наукова стаття, опублікована в липні 2009
@uk
name
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
@ast
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
@en
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
@nl
type
label
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
@ast
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
@en
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
@nl
prefLabel
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
@ast
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
@en
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
IRAP identifies an endosomal compartment required for MHC class I cross-presentation
@en
P2093
Elke Firat
Fiona Greer
Gabriele Niedermann
Mirjana Weimershaus
Oliver Carroll
Roland Kratzer
Susanna R. Keller
Vivian Lindo
P2860
P304
P3181
P356
10.1126/SCIENCE.1172845
P407
P577
2009-07-10T00:00:00Z