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Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell functionThe crystal structure of the MAP kinase LmaMPK10 from Leishmania major reveals parasite-specific features and regulatory mechanismsHigh content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discoveryVirulence of Leishmania infantum is expressed as a clonal and dominant phenotype in experimental infections.Transcriptional signatures of BALB/c mouse macrophages housing multiplying Leishmania amazonensis amastigotes.Distinct transcriptional signatures of bone marrow-derived C57BL/6 and DBA/2 dendritic leucocytes hosting live Leishmania amazonensis amastigotesFrom Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.Leishmania spp.: on the interactions they establish with antigen-presenting cells of their mammalian hosts.The enemy within: Targeting host-parasite interaction for antileishmanial drug discoveryUnveiling pathways used by Leishmania amazonensis amastigotes to subvert macrophage function.Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth.Imaging Leishmania development in their host cells.Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.Simultaneous multi-parametric analysis of Leishmania and of its hosting mammal cells: A high content imaging-based method enabling sound drug discovery process.Biological evaluation of substituted quinolines.Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses.Sorting of Leishmania-bearing dendritic cells reveals subtle parasite-induced modulation of host-cell gene expression.[Leishmania epidemiology, diagnosis, chemotherapy and vaccination approaches in the international network of Pasteur Institutes].A combined luciferase imaging and reverse transcription polymerase chain reaction assay for the study of Leishmania amastigote burden and correlated mouse tissue transcript fluctuations.The Immunomodulatory Effect of IrSPI, a Tick Salivary Gland Serine Protease Inhibitor Involved in Ixodes ricinus Tick Feeding
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description
researcher
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wetenschapper
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հետազոտող
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Eric Prina
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Eric Prina
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Eric Prina
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Eric Prina
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Eric Prina
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Eric Prina
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Eric Prina
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Eric Prina
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Eric PRINA
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Eric Prina
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Eric Prina
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Eric Prina
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Eric Prina
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P106
P31
P496
0000-0002-6888-8777