about
Neutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B)EGF receptor exposed to oxidative stress acquires abnormal phosphorylation and aberrant activated conformation that impairs canonical dimerizationLung injury and cancer: Mechanistic insights into ceramide and EGFR signaling under cigarette smoke.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury.Src mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cellsCigarette smoke induces aberrant EGF receptor activation that mediates lung cancer development and resistance to tyrosine kinase inhibitors.Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epitheliumPIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy.Cadmium induces an apoptotic response in sea urchin embryos.Environmentally relevant cadmium concentrations affect development and induce apoptosis of Paracentrotus lividus larvae cultured in vitro
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Simone Filosto
@ast
Simone Filosto
@en
Simone Filosto
@es
Simone Filosto
@nl
type
label
Simone Filosto
@ast
Simone Filosto
@en
Simone Filosto
@es
Simone Filosto
@nl
prefLabel
Simone Filosto
@ast
Simone Filosto
@en
Simone Filosto
@es
Simone Filosto
@nl
P106
P1153
16645429900
P31
P496
0000-0002-7854-998X