Cigarette smoke induces aberrant EGF receptor activation that mediates lung cancer development and resistance to tyrosine kinase inhibitors.
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Intrinsic resistance to EGFR tyrosine kinase inhibitors in advanced non-small-cell lung cancer with activating EGFR mutationsAt the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of boneThe wound healing, chronic fibrosis, and cancer progression triadCigarette smoke activates the proto-oncogene c-src to promote airway inflammation and lung tissue destruction.Lung adenocarcinoma subtypes based on expression of human airway basal cell genesAssay of lapatinib in murine models of cigarette smoke carcinogenesis.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Activation of oncogenic pathways in idiopathic pulmonary fibrosis.Lung cancer and lung injury: the dual role of ceramideSrc mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cellsSrc regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epitheliumChronic Obstructive Pulmonary Disease Is Not Associated with KRAS Mutations in Non-Small Cell Lung CancerProspective Evaluation of First-Line Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Carrying an Activating EGFR Mutation: A Multicenter Academic Phase II Study in Caucasian Patients (FIELT).JAK2 inhibitor TG101348 overcomes erlotinib-resistance in non-small cell lung carcinoma cells with mutated EGF receptor.Investigating cellular network heterogeneity and modularity in cancer: a network entropy and unbalanced motif approachPharmacological Modulation of Lung Carcinogenesis in Smokers: Preclinical and Clinical Evidence.Factors that predict progression-free survival in Chinese lung adenocarcinoma patients treated with epidermal growth factor receptor tyrosine kinase inhibitorsEGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotypeImpact of active smoking on survival of patients with metastatic lung adenocarcinoma harboring an epidermal growth factor receptor (EGFR) mutation.The impact of smoking status on radiologic tumor progression patterns and response to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors in lung adenocarcinoma with activating EGFR mutations.Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells.The biologic effects of cigarette smoke on cancer cells.The biological and clinical effects of smoking by patients with cancer and strategies to implement evidence-based tobacco cessation support.Extreme Trait Whole-Genome Sequencing Identifies PTPRO as a Novel Candidate Gene in Emphysema with Severe Airflow Obstruction.Expression of caveolin-1 is correlated with lung adenocarcinoma proliferation, migration, and invasion.Phosphorylated EGFR at tyrosine 1173 correlates with poor prognosis in oral squamous cell carcinomas.Cigarette smoke-induced EGFR activation promotes epithelial mesenchymal migration of human retinal pigment epithelial cells through regulation of the FAK-mediated Syk/Src pathway.The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistance.Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor.
P2860
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P2860
Cigarette smoke induces aberrant EGF receptor activation that mediates lung cancer development and resistance to tyrosine kinase inhibitors.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Cigarette smoke induces aberra ...... to tyrosine kinase inhibitors.
@ast
Cigarette smoke induces aberra ...... to tyrosine kinase inhibitors.
@en
type
label
Cigarette smoke induces aberra ...... to tyrosine kinase inhibitors.
@ast
Cigarette smoke induces aberra ...... to tyrosine kinase inhibitors.
@en
prefLabel
Cigarette smoke induces aberra ...... to tyrosine kinase inhibitors.
@ast
Cigarette smoke induces aberra ...... to tyrosine kinase inhibitors.
@en
P2860
P1476
Cigarette smoke induces aberra ...... to tyrosine kinase inhibitors
@en
P2093
Cathleen R Becker
Tzipora Goldkorn
P2860
P304
P356
10.1158/1535-7163.MCT-11-0698
P577
2012-02-01T00:00:00Z