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Grape-seed procyanidins act as antiinflammatory agents in endotoxin-stimulated RAW 264.7 macrophages by inhibiting NFkB signaling pathwayIdentification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (Part II): in silico prediction in antidiabetic extractsProanthocyanidins modulate microRNA expression in human HepG2 cellsDietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner.Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy.Lipogenesis is decreased by grape seed proanthocyanidins according to liver proteomics of rats fed a high fat diet.Chronic administration of proanthocyanidins or docosahexaenoic acid reverses the increase of miR-33a and miR-122 in dyslipidemic obese rats.Procyanidin effects on adipocyte-related pathologies.Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms.Nutritional biomarkers and foodomic methodologies for qualitative and quantitative analysis of bioactive ingredients in dietary intervention studies.Differential modulation of apoptotic processes by proanthocyanidins as a dietary strategy for delaying chronic pathologies.microRNAs as new targets of dietary polyphenols.Splanchnic amino acid pattern in genetic and dietary obesity in the rat.Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells.DHA sensitizes FaO cells to tert-BHP-induced oxidative effects. Protective role of EGCG.Grape seed proanthocyanidins repress the hepatic lipid regulators miR-33 and miR-122 in rats.Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes.Dietary catechins and procyanidins modulate zinc homeostasis in human HepG2 cells.Isoflavone effect on gene expression profile and biomarkers of inflammation.In vivo, in vitro, and in silico studies of Cu/Zn-superoxide dismutase regulation by molecules in grape seed procyanidin extract.Inhibitory effects of grape seed procyanidins on foam cell formation in vitro.Dietary procyanidins lower triglyceride levels signaling through the nuclear receptor small heterodimer partner.Grape seed procyanidins prevent oxidative injury by modulating the expression of antioxidant enzyme systems.Grape seed procyanidins inhibit the expression of metallothione in genes in human HepG2 cells.Differential effects of grape-seed derived procyanidins on adipocyte differentiation markers in different in vivo situationsChronic intake of proanthocyanidins and docosahexaenoic acid improves skeletal muscle oxidative capacity in diet-obese rats.Oligomers of grape-seed procyanidin extract activate the insulin receptor and key targets of the insulin signaling pathway differently from insulin.Metabolic fate of glucose on 3T3-L1 adipocytes treated with grape seed-derived procyanidin extract (GSPE). Comparison with the effects of insulin.Effects of a grapeseed procyanidin extract (GSPE) on insulin resistance.Metabolomic assessment of the effect of dietary cholesterol in the progressive development of fatty liver disease.Human apo A-I and rat transferrin are the principal plasma proteins that bind wine catechins.Grape seed procyanidins improve atherosclerotic risk index and induce liver CYP7A1 and SHP expression in healthy rats.Chronic dietary supplementation of proanthocyanidins corrects the mitochondrial dysfunction of brown adipose tissue caused by diet-induced obesity in Wistar rats.Grape seed proanthocyanidins correct dyslipidemia associated with a high-fat diet in rats and repress genes controlling lipogenesis and VLDL assembling in liver.Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet.Epigallocatechin gallate counteracts oxidative stress in docosahexaenoxic acid-treated myocytes.Grape seed proanthocyanidin extract improves the hepatic glutathione metabolism in obese Zucker rats.Detection and characterization of silver nanoparticles and dissolved species of silver in culture medium and cells by AsFlFFF-UV-Vis-ICPMS: application to nanotoxicity tests.Moderate red-wine consumption partially prevents body weight gain in rats fed a hyperlipidic diet.Chronic consumption of dietary proanthocyanidins modulates peripheral clocks in healthy and obese rats.
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