about
The cysteine-rich domain regulates ADAM protease function in vivo.Differential regulation of cell adhesive functions by integrin alpha subunit cytoplasmic tails in vivo.Integrin-ECM interactions regulate cadherin-dependent cell adhesion and are required for convergent extension in Xenopus.Integrin alpha5beta1 supports the migration of Xenopus cranial neural crest on fibronectin.FAK is required for tension-dependent organization of collective cell movements in Xenopus mesendodermDiverse functions of kindlin/fermitin proteins during embryonic development in Xenopus laevis.Identification and characterization of ADAM41, a novel ADAM metalloproteinase in Xenopus.Fibronectins, their fibrillogenesis, and in vivo functions.Roles of ADAM13-regulated Wnt activity in early Xenopus eye development.A mechanoresponsive cadherin-keratin complex directs polarized protrusive behavior and collective cell migration.Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.Integrins and cadherins join forces to form adhesive networks.ADAM13 induces cranial neural crest by cleaving class B Ephrins and regulating Wnt signalingThe extracellular matrix in development and morphogenesis: a dynamic view.Conservation and divergence of ADAM family proteins in the Xenopus genome.Patterning and tissue movements in a novel explant preparation of the marginal zone of Xenopus laevis.Multicellular computer simulation of morphogenesis: blastocoel roof thinning and matrix assembly in Xenopus laevis.Assembly and remodeling of the fibrillar fibronectin extracellular matrix during gastrulation and neurulation in Xenopus laevis.The physical state of fibronectin matrix differentially regulates morphogenetic movements in vivo.Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization.Cell adhesion receptors in mechanotransductionLive imaging of cell protrusive activity, and extracellular matrix assembly and remodeling during morphogenesis in the frog, Xenopus laevisPACSIN2 regulates cell adhesion during gastrulation in Xenopus laevis.Integrin alpha5beta1 and fibronectin regulate polarized cell protrusions required for Xenopus convergence and extension.Multiscale computational analysis of Xenopus laevis morphogenesis reveals key insights of systems-level behavior.Using Xenopus embryos to investigate integrin function.Agent-based modeling of multicell morphogenic processes during development.Cell Biology. Many modes of motility.Cloning and characterization of cDNAs encoding the integrin alpha2 and alpha3 subunits from Xenopus laevis.Separation of neural induction and neurulation in Xenopus.Concanavalin A and wheat germ agglutinin binding to sea urchin embryo basal laminae.Xenopus ADAM 13 is a metalloprotease required for cranial neural crest-cell migration.Mesendoderm extension and mantle closure in Xenopus laevis gastrulation: combined roles for integrin alpha(5)beta(1), fibronectin, and tissue geometry.Mechanical and signaling roles for keratin intermediate filaments in the assembly and morphogenesis of Xenopus mesendoderm tissue at gastrulation.Integrin alpha 5 during early development of Xenopus laevis.V(+)-fibronectin expression and localization prior to gastrulation in Xenopus laevis embryos.The RGD-dependent and the Hep II binding domains of fibronectin govern the adhesive behaviors of amphibian embryonic cellsCharacterization of convergent thickening, a major convergence force producing morphogenic movement in amphibiansIntegrins and cadherins join forces to form adhesive networksMicromere-specific cell surface proteins of 16-cell stage sea urchin embryos
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description
researcher
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wetenschapper
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հետազոտող
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name
Douglas W DeSimone
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Douglas W DeSimone
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Douglas W DeSimone
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Douglas W DeSimone
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type
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Douglas W DeSimone
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Douglas W DeSimone
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Douglas W DeSimone
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Douglas W DeSimone
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Douglas W DeSimone
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Douglas W DeSimone
@en
Douglas W DeSimone
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Douglas W DeSimone
@nl
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P244
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P1153
7004610999
P21
P214
P244
P31
P496
0000-0003-1926-1588
P735
P7859
lccn-n86852961