Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels. - Wikidata - wikimedia - TriplyDB

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.

http://www.wikidata.org/entity/Q30425400

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Gap junctional regulation of signal transduction in bone cells The interaction of biological factors with mechanical signals in bone adaptation: recent developments Functions of the osteocyte network in the regulation of bone mass Osteocytes: master orchestrators of bone Connexin 43 hemichannels and intracellular signaling in bone cells Physiological mechanisms and therapeutic potential of bone mechanosensing.14-3-3θ facilitates plasma membrane delivery and function of mechanosensitive connexin 43 hemichannels E-cadherin-mediated force transduction signals regulate global cell mechanics Local VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers.Evaluation of the Genetic Response of U937 and Jurkat Cells to 10-Nanosecond Electrical Pulses (nsEP).Differentiating connexin hemichannels and pannexin channels in cellular ATP release.Direct regulation of osteocytic connexin 43 hemichannels through AKT kinase activated by mechanical stimulation Optimal intensity shock wave promotes the adhesion and migration of rat osteoblasts via integrin β1-mediated expression of phosphorylated focal adhesion kinase.Mechanosensory responses of osteocytes to physiological forces occur along processes and not cell body and require αVβ3 integrin Cellular mechanisms of tissue fibrosis. 6. Purinergic signaling and response in fibroblasts and tissue fibrosis Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways.High flow conditions increase connexin43 expression in a rat arteriovenous and angioinductive loop model Gap junctional communication in osteocytes is amplified by low intensity vibrations in vitro.Cx43 and mechanotransduction in bone.Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture.Connexins and pannexins in the skeleton: gap junctions, hemichannels and more Osteocyte signaling in bone Role of connexins and pannexins during ontogeny, regeneration, and pathologies of bone Biological role of connexin intercellular channels and hemichannels Bone and skeletal muscle: Key players in mechanotransduction and potential overlapping mechanisms.Connexin43 and pannexin1 channels in osteoblasts: who is the "hemichannel"?"INTEGRINating" the connexin hemichannel function in bone osteocytes through the action of integrin α5 Beyond gap junctions: Connexin43 and bone cell signaling Connexins in the skeleton Connexin 43 channels protect osteocytes against oxidative stress-induced cell death.Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles.Antibodies targeting extracellular domain of connexins for studies of hemichannels The osteocyte: an endocrine cell ... and more.Connexin43 modulates post-natal cortical bone modeling and mechano-responsiveness.Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways.An intact connexin43 is required to enhance signaling and gene expression in osteoblast-like cells.Corneal Endothelial Cell Integrity in Precut Human Donor Corneas Enhanced by Autocrine Vasoactive Intestinal Peptide.Sclerostin's role in bone's adaptive response to mechanical loading.Effects of anti-sclerostin antibody and running on bone remodeling and strength.Signaling pathways affecting skeletal health.

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P2860

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.

http://www.wikidata.org/entity/Q30425400

description

2012 nî lūn-bûn

@nan

2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի փետրվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

@wuu

name

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.

@ast

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.

@en

type

label

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.

@ast

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.

@en

prefLabel

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.

@ast

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.

@en

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PNAS.1115967109

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels

@en

P2093

Arlene J Siller-Jackson

http://www.w3.org/2001/XMLSchema#string

Eileen M Lafer

http://www.w3.org/2001/XMLSchema#string

Eugene Sprague

http://www.w3.org/2001/XMLSchema#string

Gregory F Weber

http://www.w3.org/2001/XMLSchema#string

Jean X Jiang

http://www.w3.org/2001/XMLSchema#string

Lynda F Bonewald

http://www.w3.org/2001/XMLSchema#string

Nidhi Batra

http://www.w3.org/2001/XMLSchema#string

Sirisha Burra

http://www.w3.org/2001/XMLSchema#string

Sumin Gu

http://www.w3.org/2001/XMLSchema#string

Xuechun Xia

http://www.w3.org/2001/XMLSchema#string

P2860

Expression of alpha and beta subunits of the integrin superfamily in articular cartilage from macroscopically normal and osteoarthritic human femoral heads

Integrins in mechanotransduction

Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

The alpha v beta 1 integrin functions as a fibronectin receptor but does not support fibronectin matrix assembly and cell migration on fibronectin

Integrin activation and matrix binding mediate cellular responses to mechanical stretch.

Matrix-specific suppression of integrin activation in shear stress signaling.

Patterns of integrin expression in a human mandibular explant model of osteoblast differentiation.

Calcium-dependent open/closed conformations and interfacial energy maps of reconstituted hemichannels.

Prostaglandin promotion of osteocyte gap junction function through transcriptional regulation of connexin 43 by glycogen synthase kinase 3/beta-catenin signaling.

Fluid and Solute Transport in Bone: Flow-Induced Mechanotransduction

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3359-3364

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scholarly article

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10.1073/PNAS.1115967109

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P407

P433

9

http://www.w3.org/2001/XMLSchema#string

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109

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Douglas W DeSimone

Martin A Schwartz

P577

2012-02-13T00:00:00Z

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P5875

221830085

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22331870

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P921

Gap junction protein, alpha 1

Integrin alpha 5 (fibronectin receptor alpha)

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3295295

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