Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling - Wikidata - wikimedia - TriplyDB

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

http://www.wikidata.org/entity/Q56897808

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An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitination The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1 Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation Direct activation of protein kinases by unanchored polyubiquitin chains Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-α Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation Ubiquitin signaling in immune responses NF-κB, the first quarter-century: remarkable progress and outstanding questions Linear ubiquitination signals in adaptive immune responses Characterization of a UBC13 kinase in Plasmodium falciparum Protein-protein interaction antagonists as novel inhibitors of non-canonical polyubiquitylation Comprehensive logic based analyses of Toll-like receptor 4 signal transduction pathway TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.Genome wide linkage study, using a 250K SNP map, of Plasmodium falciparum infection and mild malaria attack in a Senegalese population.The IKK complex, a central regulator of NF-kappaB activation Signaling to NF-kappaB: regulation by ubiquitination.Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines.Molecular identification and interaction assay of the gene (OsUbc13) encoding a ubiquitin-conjugating enzyme in rice.Constructing and decoding unconventional ubiquitin chains.TR-FRET-based high-throughput screening assay for identification of UBC13 inhibitors.Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A.Emerging complexity of protein ubiquitination in the NF-κB pathway.MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling.Experimental verification and molecular basis of active immunization against fungal pathogens in termites.Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes Ubiquitin makes its mark on immune regulation.Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF.STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.Lysine 63-linked ubiquitination is important for arachidonic acid-induced cellular adhesion and migration.Polyubiquitination events mediate polymethylmethacrylate (PMMA) particle activation of NF-kappaB pathway Dendritic cells from humans with hypomorphic mutations in IKBKG/NEMO have impaired mitogen-activated protein kinase activity.ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18.Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ.IKKβ in postnatal perichondrium remotely controls endochondral ossification of the growth plate through downregulation of MCP-5.Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF-α-induced JNK activation and inflammation.

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Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

http://www.wikidata.org/entity/Q56897808

description

im Juli 2006 veröffentlichter wissenschaftlicher Artikel

@de

wetenschappelijk artikel

@nl

наукова стаття, опублікована в липні 2006

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name

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

@en

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

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type

label

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

@en

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

@nl

prefLabel

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

@en

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

@nl

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Nature Immunology

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Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

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Hideki Sanjo

http://www.w3.org/2001/XMLSchema#string

Kiyoshi Takeda

http://www.w3.org/2001/XMLSchema#string

Masahiro Yamamoto

http://www.w3.org/2001/XMLSchema#string

Osamu Takeuchi

http://www.w3.org/2001/XMLSchema#string

Satoshi Uematsu

http://www.w3.org/2001/XMLSchema#string

Shintaro Sato

http://www.w3.org/2001/XMLSchema#string

Shizuo Akira

http://www.w3.org/2001/XMLSchema#string

Shoji Yamaoka

http://www.w3.org/2001/XMLSchema#string

Taro Kawai

http://www.w3.org/2001/XMLSchema#string

Tatsuya Saitoh

http://www.w3.org/2001/XMLSchema#string

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962-970

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scholarly article

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10.1038/NI1367

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9

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7

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Hiroaki Sakurai

Yoshiharu Matsuura

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2006-07-23T00:00:00Z

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16862162

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