Inhibition of MDM2 via Nutlin-3A: A Potential Therapeutic Approach for Pleural Mesotheliomas with MDM2-Induced Inactivation of Wild-Type P53

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Inhibition of MDM2 via Nutlin-3A: A Potential Therapeutic Approach for Pleural Mesotheliomas with MDM2-Induced Inactivation of Wild-Type P53

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wetenschappelijk artikel

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наукова стаття, опублікована у 2018

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Inhibition of MDM2 via Nutlin- ...... Inactivation of Wild-Type P53

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Inhibition of MDM2 via Nutlin- ...... Inactivation of Wild-Type P53

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Inhibition of MDM2 via Nutlin- ...... Inactivation of Wild-Type P53

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Inhibition of MDM2 via Nutlin- ...... Inactivation of Wild-Type P53

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Inhibition of MDM2 via Nutlin- ...... Inactivation of Wild-Type P53

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Inhibition of MDM2 via Nutlin- ...... Inactivation of Wild-Type P53

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P1476

Inhibition of MDM2 via Nutlin- ...... Inactivation of Wild-Type P53

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P2093

Agnes Bankfalvi

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Daniel C Christoph

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Elena Mairinger

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Jens Kollmeier

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Jeremias Wohlschlaeger

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Kurt W Schmid

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Robert Werner

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Thomas Hager

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Thomas Mairinger

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Till Plönes

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P2860

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

Visualization and targeted disruption of protein interactions in living cells

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.

P53-MDM2 Pathway: Evidences for A New Targeted Therapeutic Approach in B-Acute Lymphoblastic Leukemia

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

P304

1986982

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scholarly article

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10.1155/2018/1986982

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English

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2018

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P577

2018-07-17T00:00:00Z

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30112000

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P932

6077509

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