A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization
about
Computer-based prediction of the drug proarrhythmic effect: problems, issues, known and suspected challengesA novel and lethal de novo LQT-3 mutation in a newborn with distinct molecular pharmacology and therapeutic responseTox-database.net: a curated resource for data describing chemical triggered in vitro cardiac ion channels inhibition.Congenital long QT syndromes: clinical features, molecular genetics and genetic testing.Overlapping LQT1 and LQT2 phenotype in a patient with long QT syndrome associated with loss-of-function variations in KCNQ1 and KCNH2Electrophysiological study of V535M hERG mutation of LQT2.Genetic testing of inherited arrhythmias.Protective effect of KCNH2 single nucleotide polymorphism K897T in LQTS families and identification of novel KCNQ1 and KCNH2 mutations.Drug-induced QT interval shortening: potential harbinger of proarrhythmia and regulatory perspectives.Individual QT-R-R relationship: average stability over time does not rule out an individual residual variability: implication for the assessment of drug effect on the QT interval.A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERGGenetic polymorphisms in KCNQ1, HERG, KCNE1 and KCNE2 genes in the Chinese, Malay and Indian populations of SingaporePossible interethnic differences in quinidine-induced QT prolongation between healthy Caucasian and Korean subjectsLong QT syndrome: reduced repolarization reserve and the genetic link.Pharmacogenetic issues in thorough QT trials.The human ERG1 channel polymorphism, K897T, creates a phosphorylation site that inhibits channel activity.The primary arrhythmia syndromes: same mutation, different manifestations. Are we starting to understand why?Iloperidone: a new option for the treatment of schizophrenia.Long QT syndrome: beyond the causal mutation.Allelic Complexity in Long QT Syndrome: A Family-Case Study.Cardiac ion channel gene mutations in sudden infant death syndrome.Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics.Molecular analysis of potassium ion channel genes in sudden death cases among patients administered psychotropic drug therapy: are polymorphisms in LQT genes a potential risk factor?Molecular and functional characterization of common polymorphisms in HERG (KCNH2) potassium channels.HealthTwiSt: the Berlin Twin Registry for health research.Common variation in NOS1AP and KCNH2 genes and QT interval duration in young adults. The Cardiovascular Risk in Young Finns Study.Drug challenge with epinephrine or isoproterenol for diagnosing a long QT syndrome: should we try this at home?Influence of genetic modifiers on sudden cardiac death cases.Functional significance of KCNH2 (HERG) K897T polymorphism for cardiac repolarization assessed by analysis of T-wave morphology.herg1b expression as a potential specific marker in pediatric acute myeloid leukemia patients with HERG 897K/K genotype.The non-synonymous coding IKr-channel variant KCNH2-K897T is associated with atrial fibrillation: results from a systematic candidate gene-based analysis of KCNH2 (HERG)Potassium channel KCNH2 K897T polymorphism and cardiac repolarization during exercise test: The Finnish Cardiovascular Study
P2860
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P2860
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization
description
im Juli 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 01 July 2003
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в липні 2003
@uk
name
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization
@en
A common polymorphism in KCNH2
@nl
type
label
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization
@en
A common polymorphism in KCNH2
@nl
prefLabel
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization
@en
A common polymorphism in KCNH2
@nl
P2093
P50
P1476
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization
@en
P2093
Andreas Jeron
Connie R Bezzina
Hanno L Tan
Heribert Schunkert
Marcel M A M Mannens
Ronald Wilders
Tamara T Koopmann
Zahurul A Bhuiyan
P356
10.1016/S0008-6363(03)00342-0
P577
2003-07-01T00:00:00Z