Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics. - Wikidata - wikimedia - TriplyDB

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics.

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics.

http://www.wikidata.org/entity/Q42260847

about

Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Afford New Opportunities in Inherited Cardiovascular Disease Modeling Inherited arrhythmias: The cardiac channelopathies Induced pluripotent stem cells for cardiovascular disease: from product-focused disease modeling to process-focused disease discovery Cardiovascular Disease Modeling Using Patient-Specific Induced Pluripotent Stem Cells Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening Translating stem cell research to cardiac disease therapies: pitfalls and prospects for improvement Disease modeling and cell based therapy with iPSC: future therapeutic option with fast and safe application Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes Modeling tissue- and mutation- specific electrophysiological effects in the long QT syndrome: role of the Purkinje fiber Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing The disease-specific phenotype in cardiomyocytes derived from induced pluripotent stem cells of two long QT syndrome type 3 patients.Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia.Modeling Inherited Arrhythmia Disorders Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes.From Bench to Market: Preparing Human Pluripotent Stem Cells Derived Cardiomyocytes for Various Applications Investigating human disease using stem cell models.iPCS Cell Modeling of Inherited Cardiac Arrhythmias.Human stem cells for modeling heart disease and for drug discovery.Genome-wide association studies and contribution to cardiovascular physiology iPSC technology--Powerful hand for disease modeling and therapeutic screen Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes Automated Electrophysiological and Pharmacological Evaluation of Human Pluripotent Stem Cell-Derived Cardiomyocytes.The investigation of sudden arrhythmic death syndrome (SADS)-the current approach to family screening and the future role of genomics and stem cell technology.Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells.Use of induced pluripotent stem cells to recapitulate pulmonary alveolar proteinosis pathogenesis.Induced pluripotent stem cell-derived cardiomyocytes: boutique science or valuable arrhythmia model?Cardiac sodium channelopathy associated with SCN5A mutations: electrophysiological, molecular and genetic aspects.Induced pluripotent stem cells as cardiac arrhythmic in vitro models and the impact for drug discovery.Pluripotent stem cells as a platform for cardiac arrhythmia drug screening Deranged sodium to sudden death.Cardiac disease modeling using induced pluripotent stem cell-derived human cardiomyocytes.Cardiomyopathy in a dish: using human inducible pluripotent stem cells to model inherited cardiomyopathies.Human induced pluripotent stem cell for modeling cardiovascular diseases.Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model for Heart Development and Congenital Heart Disease.Genetics of long-QT syndrome.Generating patient-specific induced pluripotent stem cells-derived cardiomyocytes for the treatment of cardiac diseases.From iPSC towards cardiac tissue-a road under construction.

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P2860

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics.

http://www.wikidata.org/entity/Q42260847

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Induced pluripotent stem cells ...... family with complex genetics.

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Induced pluripotent stem cells ...... family with complex genetics.

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Induced pluripotent stem cells ...... family with complex genetics.

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Induced pluripotent stem cells ...... family with complex genetics.

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The Journal of General Physiology

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Induced pluripotent stem cells ...... family with complex genetics.

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P2093

Amel Omari

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Cecile Terrenoire

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Jonathan T Lu

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Kai Wang

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Kelvin W Chan Tung

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Kevin J Sampson

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Robert H Pass

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Robert S Kass

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Wendy K Chung

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P2860

A structural basis for drug-induced long QT syndrome

A novel and lethal de novo LQT-3 mutation in a newborn with distinct molecular pharmacology and therapeutic response

Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines

Modelling the long QT syndrome with induced pluripotent stem cells

Patient-specific induced pluripotent stem-cell models for long-QT syndrome

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms

Long QT syndrome with compound mutations is associated with a more severe phenotype: a Japanese multicenter study.

Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy.

Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndrome

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61-72

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scholarly article

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10.1085/JGP.201210899

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1

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141

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Darrell N Kotton

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2013-01-01T00:00:00Z

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234019856

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23277474

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3536519

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