about
AROS has a context-dependent effect on SIRT1Screen of pseudopeptidic inhibitors of human sirtuins 1-3: two lead compounds with antiproliferative effects in cancer cells.Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptorSimvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells.N-Acylethanolamines Bind to SIRT6Transcriptomic Analysis of Human Primary Bronchial Epithelial Cells after Chloropicrin Treatment.Simvastatin induces insulin resistance in L6 skeletal muscle myotubes by suppressing insulin signaling, GLUT4 expression and GSK-3β phosphorylation.Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists.BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses.Chroman-4-one- and chromone-based sirtuin 2 inhibitors with antiproliferative properties in cancer cells.Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation.Virtual screening approach of sirtuin inhibitors results in two new scaffolds.Melatonin receptor genes.An inter-laboratory validation of methods of lipid peroxidation measurement in UVA-treated human plasma samples.Natural thermal adaptation increases heat shock protein levels and decreases oxidative stress.Important amino acids for the function of the human MT1 melatonin receptor.The functional role of cysteines adjacent to the NRY motif of the human MT1 melatonin receptor.Plant-derived compounds strigolactone GR24 and pinosylvin activate SIRT1 and enhance glucose uptake in rat skeletal muscle cells.Strigolactone GR24 and pinosylvin attenuate adipogenesis and inflammation of white adipocytes.Suppressed heat shock protein response in the kidney of exercise-trained diabetic rats.A rhodopsin-based model for melatonin recognition at its G protein-coupled receptorMutagenesis of human Mel1a melatonin receptor expressed in yeast reveals domains important for receptor functionTreatments with sodium selenate or doxycycline offset diabetes-induced perturbations of thioredoxin-1 levels and antioxidant capacityStudying SIRT6 regulation using H3K56 based substrate and small moleculesStructural properties for selective and efficient l-type amino acid transporter 1 (LAT1) mediated cellular uptakeImpact of structurally diverse BET inhibitors on SIRT1Strigolactone GR24 upregulates target genes of the cytoprotective transcription factor Nrf2 in skeletal musclePredicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Tarja Kokkola
@ast
Tarja Kokkola
@en
Tarja Kokkola
@es
Tarja Kokkola
@nl
type
label
Tarja Kokkola
@ast
Tarja Kokkola
@en
Tarja Kokkola
@es
Tarja Kokkola
@nl
prefLabel
Tarja Kokkola
@ast
Tarja Kokkola
@en
Tarja Kokkola
@es
Tarja Kokkola
@nl
P106
P1153
6507383816
P31
P496
0000-0002-3303-3912