Pulling chromatin fibers: computer simulations of direct physical micromanipulations
about
Binding of DNA-bending non-histone proteins destabilizes regular 30-nm chromatin structure.Electrostatic mechanism of nucleosomal array folding revealed by computer simulation.Chromatin fiber dynamics under tension and torsionHierarchies in eukaryotic genome organization: Insights from polymer theory and simulations.New insights into unwrapping DNA from the nucleosome from a single-molecule optical tweezers method.DNA folding: structural and mechanical properties of the two-angle model for chromatinComputer simulation of the 30-nanometer chromatin fiber.Flexible histone tails in a new mesoscopic oligonucleosome model.Evidence for heteromorphic chromatin fibers from analysis of nucleosome interactionsRole of histone tails in chromatin folding revealed by a mesoscopic oligonucleosome model.The effect of linker histone's nucleosome binding affinity on chromatin unfolding mechanisms.Theoretical methods for the simulation of nucleic acids.Keeping fingers crossed: heterochromatin spreading through interdigitation of nucleosome arrays.The chromatin fiber: multiscale problems and approaches.Forced unraveling of chromatin fibers with nonuniform linker DNA lengths.Internucleosomal interactions mediated by histone tails allow distant communication in chromatinCrucial role of dynamic linker histone binding and divalent ions for DNA accessibility and gene regulation revealed by mesoscale modeling of oligonucleosomes.Insights into chromatin fibre structure by in vitro and in silico single-molecule stretching experiments.Forces and torques in the nucleus: chromatin under mechanical constraints.Chromatin under mechanical stress: from single 30 nm fibers to single nucleosomes.Contributions of Sequence to the Higher-Order Structures of DNA.A polymer model for large-scale chromatin organization in lower eukaryotes.Exploring the conformational space of chromatin fibers and their stability by numerical dynamic phase diagrams.Nucleosome geometry and internucleosomal interactions control the chromatin fiber conformation.Computer modeling demonstrates that electrostatic attraction of nucleosomal DNA is mediated by histone tails.Can visco-elastic phase separation, macromolecular crowding and colloidal physics explain nuclear organisation?The effect of internucleosomal interaction on folding of the chromatin fiber.Multiscale modeling of nucleosome dynamics.A tale of tails: how histone tails mediate chromatin compaction in different salt and linker histone environments.Force spectroscopy of chromatin fibers: extracting energetics and structural information from Monte Carlo simulations.Chromatin: a tunable spring at work inside chromosomes.Towards quantitative analysis of gene regulation by enhancers.Transfer-matrix calculations of the effects of tension and torque constraints on DNA-protein interactions
P2860
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P2860
Pulling chromatin fibers: computer simulations of direct physical micromanipulations
description
im Januar 2000 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2000
@uk
name
Pulling chromatin fibers: computer simulations of direct physical micromanipulations
@en
Pulling chromatin fibers: computer simulations of direct physical micromanipulations
@nl
type
label
Pulling chromatin fibers: computer simulations of direct physical micromanipulations
@en
Pulling chromatin fibers: computer simulations of direct physical micromanipulations
@nl
prefLabel
Pulling chromatin fibers: computer simulations of direct physical micromanipulations
@en
Pulling chromatin fibers: computer simulations of direct physical micromanipulations
@nl
P356
P1476
Pulling chromatin fibers: computer simulations of direct physical micromanipulations
@en
P2093
Wilma K. Olson
P356
10.1006/JMBI.1999.3021
P407
P577
2000-01-01T00:00:00Z