about
Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transportSIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplexIdentification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activitiesTRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.Phospholipase A2IVα regulates phagocytosis independent of its enzymatic activityEMICORON: A multi-targeting G4 ligand with a promising preclinical profile.Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevanceDevelopment of an Optimized Protocol for NMR Metabolomics Studies of Human Colon Cancer Cell Lines and First Insight from Testing of the Protocol Using DNA G-Quadruplex Ligands as Novel Anti-Cancer Drugs.On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium saltsThe glycerophosphoinositols: cellular metabolism and biological functions.Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.A novel pathway links telomeres to NK-cell activity: Implications for immunotherapyLead Discovery of Dual G-Quadruplex Stabilizers and Poly(ADP-ribose) Polymerases (PARPs) Inhibitors: A New Avenue in Anticancer Treatment.Looking for efficient G-quadruplex ligands: evidence for selective stabilizing properties and telomere damage by drug-like molecules.Design and synthesis of a new dimeric xanthone derivative: enhancement of G-quadruplex selectivity and telomere damage.Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence.The developmentally regulated osteoblast phosphodiesterase GDE3 is glycerophosphoinositol-specific and modulates cell growth.The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses.Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.Glycerophosphoinositol-4-phosphate enhances SDF-1α-stimulated T-cell chemotaxis through PTK-dependent activation of VavIdentification of novel interactors of human telomeric G-quadruplex DNAShading the TRF2 Recruiting Function: A New Horizon in Drug DevelopmentPharmacological activation of SIRT6 triggers lethal autophagy in human cancer cellsTRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironmentThe glycerophosphoinositols and their cellular functionsCancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF2Insights into telomeric G-quadruplex DNA recognition by HMGB1 proteinTailoring a lead-like compound targeting multiple G-quadruplex structures
P50
Q27329064-CA0A88F4-E36E-411A-B651-00C4A7F4153BQ33558275-0C3C06D0-EE84-471A-AE32-D9D06A04CA60Q33944520-399B686C-DCE1-416B-8EF7-381EB02989A5Q34324128-BFC1506F-41DB-4A04-8228-45D617C07C5DQ34352727-2417DBB0-844C-4C6C-9420-9CD1FE922E7FQ35089022-7A971599-939E-4BAC-B035-AF95A17FC6F3Q35956700-5E7437F2-3F1D-4D49-9041-408FFDDFD330Q36190833-031DB707-A991-4740-9306-BEDF4D92C758Q36262988-3361CFF8-3980-4AF5-B045-AB1186BB8582Q36627895-9FEB416F-694A-42B3-A689-5C6D29806AE5Q36741609-4E9C4D1C-D966-4185-AFA1-B4FA94BEDC38Q37360409-29000795-3A4A-4219-9178-41C3638C7525Q37577613-64F2C35A-6AB9-407C-8215-EE2BB9927E49Q37631817-7FD20CFA-6BC3-491B-A34F-50BA0A35A6BDQ37652782-8D9668C3-911B-4E36-BAAB-6ADA077E5E16Q38705998-BF897A0B-721D-468D-B657-17F9CE699907Q38908244-26981057-10A4-4A9D-97FF-3E9B989D020DQ38943368-07BE5996-37C9-4E60-8D32-F2EE00183901Q39060815-4885C25B-F05A-43EA-B6BF-326DC1A600B6Q39825827-5A26EBF0-FA44-4847-8D6C-742980E4256BQ40178266-64FA5F49-9381-4C54-AB87-4D7A831AEECBQ43144870-23F27A31-8288-41E8-AF32-F8B38A66B242Q57360034-4881D7AF-E209-4707-8C5C-CD54BC8FD9B2Q57976319-DFDE8A64-86F0-4D25-B859-E316496A7B59Q57976340-D3B4A2C3-B336-46EC-8516-9B8DCB0B2AFDQ58700498-369BACC7-0EF1-41CC-8578-1F5A10CB3144Q64230103-B5424F4D-6B8E-4789-96B7-B74DC14F7001Q83284634-47A6EADC-8899-4554-B63F-85A8F9CE1F18Q89996479-C09CFC5F-1D88-4445-B269-8BA73A75F8FDQ90029047-F027F95D-44F9-45BE-9D63-021BD40E1603Q90358679-5C5DB3C8-8924-4D08-A787-DC1445D59620
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Pasquale Zizza
@ast
Pasquale Zizza
@en
Pasquale Zizza
@es
Pasquale Zizza
@nl
type
label
Pasquale Zizza
@ast
Pasquale Zizza
@en
Pasquale Zizza
@es
Pasquale Zizza
@nl
prefLabel
Pasquale Zizza
@ast
Pasquale Zizza
@en
Pasquale Zizza
@es
Pasquale Zizza
@nl
P106
P1153
56439828900
P21
P31
P496
0000-0001-7281-6090