about
HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosisPrenylation inhibitors stimulate both estrogen receptor alpha transcriptional activity through AF-1 and AF-2 and estrogen receptor beta transcriptional activity.Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways.A new protein-protein interaction sensor based on tripartite split-GFP associationOncologic trogocytosis of an original stromal cells induces chemoresistance of ovarian tumoursSymbolic data analysis to defy low signal-to-noise ratio in microarray data for breast cancer prognosis.Reversible inactivation of the transcriptional function of P53 protein by farnesylation.Synthesis and application of a N-1' fluorescent biotinyl derivative inducing the specific carboxy-terminal dual labeling of a novel RhoB-selective scFv.Preferential transfer of certain plasma membrane proteins onto T and B cells by trogocytosis.Melanoma cells treated with GGTI and IFN-gamma allow murine vaccination and enhance cytotoxic response against human melanoma cells.Single domain antibodies with VH hallmarks are positively selected during panning of llama (Lama glama) naïve libraries.Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line A549.Targeted identification of sialoglycoproteins in hypoxic endothelial cells and validation in zebrafish reveal roles for proteins in angiogenesisFuzzy logic selection as a new reliable tool to identify molecular grade signatures in breast cancer--the INNODIAG studyGeneration of a single chain antibody variable fragment (scFv) to sense selectively RhoB activation.SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction.NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies.Melanoma-expressed CD70 is involved in invasion and metastasis.DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.The RAS-related GTPase RHOB confers resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung cancer via an AKT-dependent mechanism.RhoB loss induces Rac1-dependent mesenchymal cell invasion in lung cells through PP2A inhibition.RhoB promotes γH2AX dephosphorylation and DNA double-strand break repairFormation of the eIF4F translation-initiation complex determines sensitivity to anticancer drugs targeting the EGFR and HER2 receptors.In vivo restoration of RhoB expression leads to ovarian tumor regression.MAP1A light chain-2 interacts with GTP-RhoB to control epidermal growth factor (EGF)-dependent EGF receptor signaling.The prototypical inhibitor of cholesterol esterification, Sah 58-035 [3-[decyldimethylsilyl]-n-[2-(4-methylphenyl)-1-phenylethyl]propanamide], is an agonist of estrogen receptors.Monitoring KRAS mutations in circulating DNA and tumor cells using digital droplet PCR during treatment of KRAS-mutated lung adenocarcinoma.Geranylgeranyl transferase inhibition stimulates anti-melanoma immune response through MHC Class I and costimulatory molecule expression.Coexpression of CD40L and CD70 by semiallogenic tumor cells induces anti-tumor immunity.Induction of T-cell antitumor immunity and protection against tumor growth by secretion of soluble human CD70 molecules.Loss of RhoB expression in human lung cancer progression.Inhibition of Rho pathways induces radiosensitization and oxygenation in human glioblastoma xenografts.Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation.Involvement of tyrosine kinase activity in the low-density lipoprotein receptor expression in human lung adenocarcinoma cell line A549.Evidence for up-regulated low density lipoprotein receptor in human lung adenocarcinoma cell line A549.RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription.Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228.Tipifarnib plus tamoxifen in tamoxifen-resistant metastatic breast cancer: a negative phase II and screening of potential therapeutic markers by proteomic analysis.The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit.Proliferative effect of high density lipoprotein (HDL) and HDL fractions (HDL1,2, HDL3) on virus transformed lymphoblastoid cells.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Gilles Favre
@ast
Gilles Favre
@en
Gilles Favre
@es
Gilles Favre
@nl
type
label
Gilles Favre
@ast
Gilles Favre
@en
Gilles Favre
@es
Gilles Favre
@nl
prefLabel
Gilles Favre
@ast
Gilles Favre
@en
Gilles Favre
@es
Gilles Favre
@nl
P106
P31
P496
0000-0002-2344-1883