Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line A549.
about
Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysisNovel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statinsTumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancerLocalization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cellsNon-lipid-related effects of statins.Synergic effect of eicosapentaenoic acid and lovastatin on gene expression of HMGCoA reductase and LDL receptor in cultured HepG2 cellsElevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agents.p53 regulates the mevalonate pathway in human glioblastoma multiforme.Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth.Synergistic Impact of d-δ-Tocotrienol and Geranylgeraniol on the Growth and HMG CoA Reductase of Human DU145 Prostate Carcinoma Cells.β-ionone induces cell cycle arrest and apoptosis in human prostate tumor cells.Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial.Simvastatin stimulates apoptosis in cholangiocarcinoma by inhibition of Rac1 activity.Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancer.Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2.Lovastatin induces apoptosis in malignant mesothelioma cells.Tyrosine kinase-dependent modulation of 3-hydroxy-3-methylglutaryl-CoA reductase in human breast adenocarcinoma SKBR-3 cellsMolecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation.Lipid metabolic pathways as lung cancer therapeutic targets: a computational study.Chemical-physical changes in cell membrane microdomains of breast cancer cells after omega-3 PUFA incorporation.Modification of phospholipids fatty acid composition in reuber H35 hepatoma cells: effect on HMG-CoA reductase activity.Mevalonate promotes the growth of tumors derived from human cancer cells in vivo and stimulates proliferation in vitro with enhanced cyclin-dependent kinase-2 activity.Correlation between use of simvastatin and lovastatin and female lung cancer risk: a nationwide case-control study.Chemoprevention by pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, of N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats.
P2860
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P2860
Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line A549.
description
1993 nî lūn-bûn
@nan
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Importance of mevalonate-deriv ...... adenocarcinoma cell line A549.
@ast
Importance of mevalonate-deriv ...... adenocarcinoma cell line A549.
@en
Importance of mevalonate-deriv ...... adenocarcinoma cell line A549.
@nl
type
label
Importance of mevalonate-deriv ...... adenocarcinoma cell line A549.
@ast
Importance of mevalonate-deriv ...... adenocarcinoma cell line A549.
@en
Importance of mevalonate-deriv ...... adenocarcinoma cell line A549.
@nl
prefLabel
Importance of mevalonate-deriv ...... adenocarcinoma cell line A549.
@ast
Importance of mevalonate-deriv ...... adenocarcinoma cell line A549.
@en
Importance of mevalonate-deriv ...... adenocarcinoma cell line A549.
@nl
P2093
P2860
P356
P1476
Importance of mevalonate-deriv ...... adenocarcinoma cell line A549
@en
P2093
P2860
P304
P356
10.1002/IJC.2910550421
P50
P577
1993-10-01T00:00:00Z