Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration
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Colesevelam hydrochloride: evidence for its use in the treatment of hypercholesterolemia and type 2 diabetes mellitus with insights into mechanism of actionNuclear receptor LRH-1 induces the reproductive neuropeptide kisspeptin in the hypothalamus.Identification of transcription factors and single nucleotide polymorphisms of Lrh1 and its homologous genes in Lrh1-knockout pancreas of mice.Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut MicrobiotaLRH-1-dependent glucose sensing determines intermediary metabolism in liver.Transcriptional regulation of Niemann-Pick C1-like 1 gene by liver receptor homolog-1.LRH-1-dependent programming of mitochondrial glutamine processing drives liver cancer.The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.An overview of transcriptional regulation in response to toxicological insult.SEURAT-1 liver gold reference compounds: a mechanism-based review.Human FXR regulates SHP expression through direct binding to an LRH-1 binding site, independent of an IR-1 and LRH-1.Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota.Activation of PPARα decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion.Prostaglandin E2 promotes hepatic bile acid synthesis by an E prostanoid receptor 3-mediated hepatocyte nuclear receptor 4α/cholesterol 7α-hydroxylase pathway in mice.The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice.Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of Cyp7a1.
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Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration
description
article
@en
im Juni 2011 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в червні 2011
@uk
name
Liver receptor homolog-1 is cr ...... during bile salt sequestration
@en
Liver receptor homolog-1 is cr ...... during bile salt sequestration
@nl
type
label
Liver receptor homolog-1 is cr ...... during bile salt sequestration
@en
Liver receptor homolog-1 is cr ...... during bile salt sequestration
@nl
prefLabel
Liver receptor homolog-1 is cr ...... during bile salt sequestration
@en
Liver receptor homolog-1 is cr ...... during bile salt sequestration
@nl
P2093
P2860
P356
P1433
P1476
Liver receptor homolog-1 is cr ...... during bile salt sequestration
@en
P2093
Albert K Groen
Carolien Out
Folkert Kuipers
Han Gerrits
Jurre Hageman
Maarten D Sollewijn Gelpke
Martin J Smit
Rick Havinga
Trijnie Bos
P2860
P304
P356
10.1002/HEP.24286
P407
P577
2011-06-01T00:00:00Z