Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen
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A model of anthrax toxin lethal factor bound to protective antigen.Tumor Targeting and Drug Delivery by Anthrax ToxinPoint mutations in anthrax protective antigen that block translocation.Membrane insertion: The strategies of toxins (review).Designing a polyvalent inhibitor of anthrax toxin.The seminal literature of anthrax research.The p53 tumour suppressor protein.Anthrax lethal factor represses glucocorticoid and progesterone receptor activity.Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases.G protein-coupled receptor oligomerization provides the framework for signal discrimination.p53 tumor suppressor gene: a critical molecular target for UV induction and prevention of skin cancer.Regulation of p53--insights into a complex process.Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel.The effect of C-terminal fragment of JNK2 on the stability of p53 and cell proliferation.The host cell chaperone Hsp90 is essential for translocation of the binary Clostridium botulinum C2 toxin into the cytosol.Participation of residue F552 in domain III of the protective antigen in the biological activity of anthrax lethal toxin.Eiger-induced cell death relies on Rac1-dependent endocytosisChloroquine derivatives block the translocation pores and inhibit cellular entry of Clostridium botulinum C2 toxin and Bacillus anthracis lethal toxin.Mediation by arachidonic acid metabolites of the H2O2-induced stimulation of mitogen-activated protein kinases (extracellular-signal-regulated kinase and c-Jun NH2-terminal kinase).Mapping the anthrax protective antigen binding site on the lethal and edema factors.Purified Bacillus anthracis lethal toxin complex formed in vitro and during infection exhibits functional and biological activity.Anthrax biosensor, protective antigen ion channel asymmetric blockade.Whole-cell voltage clamp measurements of anthrax toxin pore current.
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P2860
Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im August 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в серпні 1995
@uk
name
Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen
@en
Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen
@nl
type
label
Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen
@en
Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen
@nl
prefLabel
Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen
@en
Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen
@nl
P2860
P356
P1476
Effect of anthrax toxin's lethal factor on ion channels formed by the protective antigen
@en
P2093
P2860
P304
18626-18630
P356
10.1074/JBC.270.31.18626
P407
P577
1995-08-01T00:00:00Z