Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+T Cells Infiltrate Islets in Type 1 Diabetes
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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targetsMolecular Interactions Governing Autoantigen Presentation in Type 1 DiabetesRegulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects.Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.Prediction and prevention of type 1 diabetes: update on success of prediction and struggles at preventionPathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusionObstacles and opportunities for targeting the effector T cell response in type 1 diabetes.Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetesAnalysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.Narrowing in on the anti-β cell-specific T cells: looking 'where the action is'.CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.Tolerogenic Nanoparticles to Treat Islet Autoimmunity.The Clonal Invariant NKT Cell Repertoire in People with Type 1 Diabetes Is Characterized by a Loss of Clones Expressing High-Affinity TCRs.Beta-cell specific autoantibodies: Are they just an indicator of type 1 diabetes?Memory T Cells in Type 1 Diabetes: the Devil is in the Detail.Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.Isolation of human monoclonal autoantibodies derived from pancreatic lymph node and peripheral blood B cells of islet autoantibody-positive patients.T Cell Receptor Profiling in Type 1 Diabetes.The case for an autoimmune aetiology of type 1 diabetes.Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes.T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.Human islets and dendritic cells generate post-translationally modified islet autoantigens.Deciphering the Pathogenesis of Human Type 1 Diabetes (T1D) by Interrogating T Cells from the "Scene of the Crime".Autoreactive T cells in type 1 diabetes.Pathophysiological characteristics of preproinsulin-specific CD8+ T cells in subjects with juvenile-onset and adult-onset type 1 diabetes: A 1-year follow-up study.Understanding Autoimmune Diabetes through the Prism of the Tri-Molecular Complex.Mitochondrial Reactive Oxygen Species and Type 1 Diabetes.Shuffling peptides to create T-cell epitopes: does the immune system play cards?Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes.Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate.
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Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+T Cells Infiltrate Islets in Type 1 Diabetes
description
im August 2014 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 25 August 2014
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в серпні 2014
@uk
name
Proinsulin-Specific, HLA-DQ8, ...... rate Islets in Type 1 Diabetes
@en
Proinsulin-Specific, HLA-DQ8, ...... rate Islets in Type 1 Diabetes
@nl
type
label
Proinsulin-Specific, HLA-DQ8, ...... rate Islets in Type 1 Diabetes
@en
Proinsulin-Specific, HLA-DQ8, ...... rate Islets in Type 1 Diabetes
@nl
prefLabel
Proinsulin-Specific, HLA-DQ8, ...... rate Islets in Type 1 Diabetes
@en
Proinsulin-Specific, HLA-DQ8, ...... rate Islets in Type 1 Diabetes
@nl
P2093
P356
P1433
P1476
Proinsulin-specific, HLA-DQ8, ...... rate islets in type 1 diabetes
@en
P2093
Balasubramanian Krishnamurthy
Christine Rodda
Helen E Thomas
Janine P Kuehlich
Nadine L Dudek
P Toby H Coates
Peter D Campbell
Philip Bergman
Philip J O'Connell
P304
P356
10.2337/DB14-0858
P407
P577
2014-08-25T00:00:00Z