about
Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity.Oleanolic acid reduces hyperglycemia beyond treatment period with Akt/FoxO1-induced suppression of hepatic gluconeogenesis in type-2 diabetic mice.Glucose homeostasis in mice is transglutaminase 2 independentQ&A: insulin secretion and type 2 diabetes: why do β-cells fail?Nuclear factor κB-inducing kinase activation as a mechanism of pancreatic β cell failure in obesity.Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.Alteration of endoplasmic reticulum lipid rafts contributes to lipotoxicity in pancreatic β-cellsThe hypoxia response pathway and β-cell function.The control of insulin secretion by adipokines: current evidence for adipocyte-beta cell endocrine signalling in metabolic homeostasis.Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells.Pancreatic PYY Is Critical in the Control of Insulin Secretion and Glucose Homeostasis in Female Mice.Sweet and sour β-cells: ROS and Hif1α induce Warburg-like lactate production during type 2 diabetes.Inhibition of Y1 receptor signaling improves islet transplant outcome.The radical-SAM enzyme Viperin catalyzes reductive addition of a 5'-deoxyadenosyl radical to UDP-glucose in vitro.The diverse roles of protein kinase C in pancreatic beta-cell function.Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice.DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake.High dietary fat and sucrose results in an extensive and time-dependent deterioration in health of multiple physiological systems in mice.Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo.Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice.Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell massCirculating AFABP promotes insulin secretionPancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
James Cantley
@ast
James Cantley
@en
James Cantley
@es
James Cantley
@nl
type
label
James Cantley
@ast
James Cantley
@en
James Cantley
@es
James Cantley
@nl
prefLabel
James Cantley
@ast
James Cantley
@en
James Cantley
@es
James Cantley
@nl
P106
P1153
12645391200
P21
P31
P496
0000-0003-2509-1271