about
FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cellsDynamic recruitment of human CD2 into lipid rafts. Linkage to T cell signal transductionSerological identification and expression analysis of gastric cancer-associated genesThe Nef protein of HIV-1 associates with rafts and primes T cells for activationStructure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactivPoor binding of a HER-2/neu epitope (GP2) to HLA-A2.1 is due to a lack of interactions with the center of the peptideNovel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 productionClonal anergy induced in a CD8+ hapten-specific cytotoxic T-cell clone by an altered hapten-peptide ligandThe B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responsesAdaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: differential involvement of the FYB SH3 domainPhage display of peptide / major histocompatibility class I complexes.Systems biology. Conditional density-based analysis of T cell signaling in single-cell data.Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile.Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells.Induction of human cytotoxic T lymphocytes by artificial antigen-presenting cells.T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.Dendritic cell biology and regulation of dendritic cell trafficking by chemokines.Gene therapy: development of immunostimulatory treatments for cancer.Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics.Antigen decoding by T lymphocytes: from synapses to fate determination.Heteromeric amino acid transporters: biochemistry, genetics, and physiology.Signalling scaffolds and adaptors in T-cell immunity.T lymphocyte activation--an inside overview.Abnormal T cell signal transduction in systemic lupus erythematosus.Tumor-specific Ab-mediated targeting of MHC-peptide complexes induces regression of human tumor xenografts in vivo.T cell receptor-ligand interactions: a conformational preequilibrium or an induced fit.The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiaeCross-priming of naive CD8 T cells against melanoma antigens using dendritic cells loaded with killed allogeneic melanoma cells.Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes.The proliferative capacity of individual naive CD4(+) T cells is amplified by prolonged T cell antigen receptor triggeringA balance between positive and negative signals in cytotoxic lymphocytes regulates the polarization of lipid rafts during the development of cell-mediated killingTransmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.Translating the concept of suppressor/regulatory T cells to clinical applications.CD4+ T-cell memory: generation and multi-faceted roles for CD4+ T cells in protective immunity to influenza.Biased epitope selection by recombinant vaccinia-virus (rVV)-infected mature or immature dendritic cellsCXCR4-CCR5: a couple modulating T cell functionsThe molecular makeup and function of regulatory and effector synapses.Lipid rafts and T-lymphocyte function: implications for autoimmunity.CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters.A combined approach of human leukocyte antigen ligandomics and immunogenicity analysis to improve peptide-based cancer immunotherapy.
P2860
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P2860
description
im Januar 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 01 January 1999
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 1999
@uk
name
From TCR Engagement to T Cell Activation
@en
From TCR Engagement to T Cell Activation
@nl
type
label
From TCR Engagement to T Cell Activation
@en
From TCR Engagement to T Cell Activation
@nl
prefLabel
From TCR Engagement to T Cell Activation
@en
From TCR Engagement to T Cell Activation
@nl
P1433
P1476
From TCR engagement to T cell activation: a kinetic view of T cell behavior
@en
P2093
A Lanzavecchia
P356
10.1016/S0092-8674(00)80952-6
P407
P50
P577
1999-01-01T00:00:00Z