Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.
about
Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) responseRole of HLA Adaptation in HIV EvolutionHepatitis C virus adaptation to T-cell immune pressureEvidence of Viral Adaptation to HLA Class I-Restricted Immune Pressure in Chronic Hepatitis C Virus InfectionMutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to manAnalysis of the Evolutionary Forces in an Immunodominant CD8 Epitope in Hepatitis C Virus at a Population LevelDistinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope SpecificityInfluence of host resistance on viral adaptation: hepatitis C virus as a case studyHuman leukocyte antigens and HIV type 1 viral load in early and chronic infection: predominance of evolving relationshipsHLA-driven convergence of HIV-1 viral subtypes B and F toward the adaptation to immune responses in human populationsAdaptive immune responses in acute and chronic hepatitis C virus infectionAdaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs.Defining epitope coverage requirements for T cell-based HIV vaccines: theoretical considerations and practical applications.Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection.Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape.Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage.Molecular evolution of human immunodeficiency virus type 1 upon transmission between human leukocyte antigen disparate donor-recipient pairs.The specificity and polymorphism of the MHC class I prevents the global adaptation of HIV-1 to the monomorphic proteasome and TAP.Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.Frequent toggling between alternative amino acids is driven by selection in HIV-1The distribution of CTL epitopes in HIV-1 appears to be random, and similar to that of other proteomes.Timing constraints of in vivo gag mutations during primary HIV-1 subtype C infectionGeneration of robust CD8+ T-cell responses against subdominant epitopes in conserved regions of HIV-1 by repertoire mining with mimotopes.High-throughput high-resolution class I HLA genotyping in East Africa.Viral adaptation to immune selection pressure by HLA class I-restricted CTL responses targeting epitopes in HIV frameshift sequences.Amino-acid co-variation in HIV-1 Gag subtype C: HLA-mediated selection pressure and compensatory dynamics.Epitope discovery with phylogenetic hidden Markov models.Detecting consistent patterns of directional adaptation using differential selection codon models.Long-term control of HIV-1 in hemophiliacs carrying slow-progressing allele HLA-B*5101Molecular characterization of HIV-1 CRF01_AE in Mekong Delta, Vietnam, and impact of T-cell epitope mutations on HLA recognition (ANRS 12159).Sexual transmission of single human immunodeficiency virus type 1 virions encoding highly polymorphic multisite cytotoxic T-lymphocyte escape variants.Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load.Impact of MHC class I diversity on immune control of immunodeficiency virus replication.Impact of HLA selection pressure on HIV fitness at a population level in Mexico and Barbados.Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection.Sequence evolution of HIV-1 following mother-to-child transmission.Early immune adaptation in HIV-1 revealed by population-level approaches.Vaccination reduces simian-human immunodeficiency virus sequence reversion through enhanced viral controlRelative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control.
P2860
Q21131580-74964A61-F26B-4AE6-8572-FDB2E7102D8EQ26772713-B50FBDC9-AE01-44AE-BA26-4113C44ADFEBQ26862729-B3F9BDDD-4BD4-4C85-A0F8-BE38519530B0Q27477614-474BAF35-B572-4E7A-8AF2-564B8CFA1C3EQ27485215-D65FC523-4F4E-4E20-BD55-4C22F73F3439Q27485493-C15BB82F-95C8-4716-95D7-F3BDB00DEBFBQ27675464-A60F6669-2D60-454E-A103-0DF6C32C3489Q28087595-0A077993-B1DE-407B-A74C-9FD40E139CBDQ28394085-D810ACA8-6CDD-4983-9BD1-2308A4A30F3CQ28473841-A83CDA93-02E1-45BD-A7E8-BAA06E0600FAQ29619722-7F44D468-B6B7-4631-8D96-777441216BB6Q30386701-29675EBD-363C-48FD-8980-2396A92BD6CDQ30410411-8B7CE36F-6B10-4CA9-A113-7E0DB74F7C02Q30469621-7CD8EF17-3CE0-42CC-93CF-2ADF20B9CC8AQ33274640-5894AA57-1C4A-4EB0-A610-DEF23A5E4278Q33290217-ADEBCFFA-4DA7-472B-8FC6-EF840C603A9BQ33325923-CFBBDA95-305A-432B-B8FC-5BA6C985B194Q33344499-783782E9-AE58-425A-8773-998233716DEEQ33379106-F7D3A265-8E7F-4B2C-A082-2AA4ED440857Q33385995-48A3519B-5A68-4C6D-AE3A-1704717F2C7DQ33394563-A657DA72-9701-447B-82F8-D5BA647262AFQ33490243-F88719F9-86C8-4483-B057-CBCCF0F39624Q33515034-3AF5C716-8AC0-406E-887E-EA1C8E7EEF51Q33568699-D8390C03-61A7-4911-8CBA-F292DD8E8CEAQ33588595-154D0F05-A47D-4ACC-92CD-561F88F94767Q33615145-47345EFC-96E4-49F4-BE54-3DA0B46F058BQ33687232-40B0E02B-134B-4714-8327-0DC0E7FDD7FAQ33803120-DCC9FCE6-B4D0-44A3-B472-88DD62A3E45EQ33827531-52AF9131-C825-476C-8E92-93FB6EA6F9CCQ33966626-F82FA479-1019-4CBE-A20E-E9F8B0096526Q34062308-0DE7AADA-760F-4B02-AD5C-A6014375DE4CQ34123849-9196AD3F-6019-4FDE-ADD4-385DEC61569BQ34197037-C8F5FC66-353E-4645-B770-DFCF4B5F65C9Q34235198-1BFFC0BE-8E99-49F7-8B6B-58008143F8ADQ34262204-74FC35C9-2491-48D8-8F2F-88A54070CBD5Q34269570-FB3556EF-78A0-474D-BE55-B41DA36B8FD2Q34291084-B5E8B890-11EA-466D-9B94-E408C841DCDCQ34308788-2742C666-5F51-4059-80A8-40D73F2EDDC3Q34416586-EF48379D-6BCF-496B-9C2C-286E9E781A40Q34435052-1841AA37-E53E-4C55-90EF-49A62BD6B003
P2860
Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Transmission and accumulation ...... een HIV polymorphisms and HLA.
@ast
Transmission and accumulation ...... een HIV polymorphisms and HLA.
@en
type
label
Transmission and accumulation ...... een HIV polymorphisms and HLA.
@ast
Transmission and accumulation ...... een HIV polymorphisms and HLA.
@en
prefLabel
Transmission and accumulation ...... een HIV polymorphisms and HLA.
@ast
Transmission and accumulation ...... een HIV polymorphisms and HLA.
@en
P2093
P2860
P50
P356
P1476
Transmission and accumulation ...... een HIV polymorphisms and HLA.
@en
P2093
Anne Edwards
Charles Edwards
Christina Thobakgale
Corey Moore
Daniel Kavanagh
Danni Ramduth
Graz Luzzi
Isobella Honeyborne
James Mullins
Karina Yusim
P2860
P304
P356
10.1084/JEM.20041455
P407
P50
P577
2005-03-01T00:00:00Z