Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis
about
Human keratinocytes have two interconvertible modes of proliferation.Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesisJarid2 regulates mouse epidermal stem cell activation and differentiationSox4 links tumor suppression to accelerated aging in mice by modulating stem cell activationKindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferationCbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium.Clonal growth of dermal papilla cells in hydrogels reveals intrinsic differences between Sox2-positive and -negative cells in vitro and in vivoEpidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factorsLoss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γMacrophages are necessary for epimorphic regeneration in African spiny mice.Directed elimination of senescent cells by inhibition of BCL-W and BCL-XLHeparan sulfate regulates hair follicle and sebaceous gland morphogenesis and homeostasis.PW1 gene/paternally expressed gene 3 (PW1/Peg3) identifies multiple adult stem and progenitor cell populations.Expression of Kruppel-like factor KLF4 in mouse hair follicle stem cells contributes to cutaneous wound healing.Estrogen leads to reversible hair cycle retardation through inducing premature catagen and maintaining telogenDistinct fibroblast lineages determine dermal architecture in skin development and repair.Markers of epidermal stem cell subpopulations in adult mammalian skin.Microfluidic Isolation of CD34-Positive Skin Cells Enables Regeneration of Hair and Sebaceous Glands In Vivo.BLIMP1 is required for postnatal epidermal homeostasis but does not define a sebaceous gland progenitor under steady-state conditions.Nucleosome organizations in induced pluripotent stem cells reprogrammed from somatic cells belonging to three different germ layers.Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis.Pleiotropic age-dependent effects of mitochondrial dysfunction on epidermal stem cellsPolyclonal origin and hair induction ability of dermal papillae in neonatal and adult mouse back skin.FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis.Protective immune responses against Schistosoma mansoni infection by immunization with functionally active gut-derived cysteine peptidases alone and in combination with glyceraldehyde 3-phosphate dehydrogenase.Profiling of Sox4-dependent transcriptome in skin links tumour suppression and adult stem cell activationmTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis.Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms.CD98hc (SLC3A2) regulation of skin homeostasis wanes with ageSpindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells.Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells.Microfluidic enrichment of mouse epidermal stem cells and validation of stem cell proliferation in vitro.Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing.Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis.In vivo functional studies of tumor-specific retrogene NanogP8 in transgenic animals.Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regenerationThe senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration.TLR7-expressing cells comprise an interfollicular epidermal stem cell population in murine epidermis.The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin.5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells.
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P2860
Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis
description
im April 2010 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 2010
@uk
name
Assaying proliferation and dif ...... gregated adult mouse epidermis
@en
Assaying proliferation and dif ...... gregated adult mouse epidermis
@nl
type
label
Assaying proliferation and dif ...... gregated adult mouse epidermis
@en
Assaying proliferation and dif ...... gregated adult mouse epidermis
@nl
prefLabel
Assaying proliferation and dif ...... gregated adult mouse epidermis
@en
Assaying proliferation and dif ...... gregated adult mouse epidermis
@nl
P50
P356
P1433
P1476
Assaying proliferation and dif ...... gregated adult mouse epidermis
@en
P2888
P304
P356
10.1038/NPROT.2010.39
P577
2010-04-22T00:00:00Z