Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer
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BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotypeEpigenetic silencing of DSC3 is a common event in human breast cancer.Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoterClinical characteristics of ovarian cancer classified by BRCA1, BRCA2, and RAD51C statusLympho-vascular invasion in BRCA related breast cancer compared to sporadic controls.Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens.DNA methylation, chromatin inheritance, and cancer.Methylation profiling of ductal carcinoma in situ and its relationship to histopathological features.Assessment of DNA methylation profiling and copy number variation as indications of clonal relationship in ipsilateral and contralateral breast cancers to distinguish recurrent breast cancer from a second primary tumourMonozygotic twins discordant for constitutive BRCA1 promoter methylation, childhood cancer and secondary cancerConstitutive promoter methylation of BRCA1 and RAD51C in patients with familial ovarian cancer and early-onset sporadic breast cancerReduced BRCA1 expression due to promoter hypermethylation in therapy-related acute myeloid leukaemiaPromoter Methylation Status of Breast Cancer Susceptibility Gene 1 and 17 Beta Hydroxysteroid Dehydrogenase Type 1 Gene in Sporadic Breast Cancer Patients.Clinical significance of epigenetic inactivation of hMLH1 and BRCA1 in Tunisian patients with invasive breast carcinoma.Novel BRCA1 and BRCA2 Tumor Test as Basis for Treatment Decisions and Referral for Genetic Counselling of Patients with Ovarian Carcinomas.Functional Impact of Sequence Alterations Found in BRCA1 Promoter/5'UTR Region in Breast/Ovarian Cancer Families from Upper Silesia, Poland.Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer.Primary squamous cell carcinoma of the endometrium unrelated to human papilloma virus: a molecular study.Impact of Etoposide on BRCA1 Expression in Various Breast Cancer Cell Lines.Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas.CD40-induced transcriptional activation of vascular endothelial growth factor involves a 68-bp region of the promoter containing a CpG island.BRCA1 promoter hypermethylation and protein expression in ovarian carcinoma--an Indian study.Loss of heterozygosity analysis at theBRCAloci in tumor samples from patients with familial breast cancerDNA repair gene inactivation in non-Hodgkin's lymphoma
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P2860
Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer
description
im Februar 2000 veröffentlichter wissenschaftlicher Artikel
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scientific article published on 01 February 2000
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wetenschappelijk artikel
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наукова стаття, опублікована в лютому 2000
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name
Tumour-specific distribution o ...... e in breast and ovarian cancer
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Tumour-specific distribution o ...... e in breast and ovarian cancer
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type
label
Tumour-specific distribution o ...... e in breast and ovarian cancer
@en
Tumour-specific distribution o ...... e in breast and ovarian cancer
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prefLabel
Tumour-specific distribution o ...... e in breast and ovarian cancer
@en
Tumour-specific distribution o ...... e in breast and ovarian cancer
@nl
P2093
P356
P1433
P1476
Tumour-specific distribution o ...... e in breast and ovarian cancer
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P2093
P304
P356
10.1093/CARCIN/21.2.147
P407
P577
2000-02-01T00:00:00Z