Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition
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Inhibition of calcineurin phosphatase activity by a calcineurin B homologous proteinTransient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathwaysTropomodulin capping of actin filaments in striated muscle development and physiologyMyosin binding protein C: implications for signal-transductionInherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosisTargeted inhibition of calcineurin attenuates cardiac hypertrophy in vivoActivation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytesElectrical stimulation of neonatal cardiac myocytes activates the NFAT3 and GATA4 pathways and up-regulates the adenylosuccinate synthetase 1 geneMaintenance of muscle mass is not dependent on the calcineurin-NFAT pathwayMammalian target of rapamycin and protein kinase A signaling mediate the cardiac transcriptional response to glutamineRequirement of transcription factor NFAT in developing atrial myocardiumConditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy.Effects of serine/threonine protein phosphatases on ion channels in excitable membranes.Androgens and the control of skeletal muscle protein synthesis.Hypertrophic cardiomyopathy: a heart in need of an energy bar?Decoding calcium signals involved in cardiac growth and function.Cardiac atrophy after bed rest and spaceflight.Calcium, calcineurin, and the control of transcription.Transcriptional regulation of cardiac development: implications for congenital heart disease and DiGeorge syndrome.Effects of the calcineurin dependent signaling pathway inhibition by cyclosporin A on early and late cardiac remodeling following myocardial infarction.Calcineurin inhibition and cardiac hypertrophy: a matter of balance.Molecular medicine in the 21st century.Requirement of the calcineurin subunit gene canB2 for indirect flight muscle formation in Drosophila.Calcineurin and hypertrophic heart disease: novel insights and remaining questions.Beta-blockers, left and right ventricular function, and in-vivo calcium influx in muscular dystrophy cardiomyopathy.Cardiac mass and function decrease in bronchiolitis obliterans syndrome after lung transplantation: relationship to physical activity?Calcineurin and cardiac hypertrophy: where have we been? Where are we going?Calcineurin phosphatase in signal transduction: lessons from fission yeast.Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo.Emerging therapeutic targets in chronic heart failure: part I.Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors.Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes.Activation of nuclear factor-kappaB is necessary for myotrophin-induced cardiac hypertrophy.The synergistic interaction between the calcineurin B subunit and IFN-γ enhances macrophage antitumor activity.Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy.An emerging role for calcineurin Aalpha in the development and function of the kidney.Tropomyosin dephosphorylation results in compensated cardiac hypertrophyGenetic engineering and therapy for inherited and acquired cardiomyopathies.Myocardial AKT: the omnipresent nexus.Targeting altered calcium physiology in the heart: translational approaches to excitation, contraction, and transcription.
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P2860
Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition
description
im September 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 01 September 1998
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 1998
@uk
name
Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition
@en
Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition
@nl
type
label
Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition
@en
Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition
@nl
prefLabel
Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition
@en
Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition
@nl
P2093
P1433
P1476
Prevention of cardiac hypertrophy in mice by calcineurin inhibition
@en
P2093
A Gualberto
D F Wieczorek
M A Sussman
M C Colbert
P304
P356
10.1126/SCIENCE.281.5383.1690
P407
P577
1998-09-01T00:00:00Z